Trpm1 - transient receptor potential cation channel, subfamily M, member 1 Gene

Also Known as Mlsn1; Ltrpc1; 4732499L03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17364

Summary

Enables cation channel activity. Involved in cellular response to light stimulus. Acts upstream of or within cellular protein localization; retinal rod cell development; and signal transduction. Located in new growing cell tip. Is expressed in foregut; reproductive system; and sensory organ. Human ortholog(s) of this gene implicated in congenital stationary night blindness and congenital stationary night blindness 1C. Orthologous to human TRPM1 (transient receptor potential cation channel subfamily M member 1). [provided by Alliance of Genome Resources, Apr 2022]

Trpm1 Products (2)

mRNA Protein Name
NM_001039104.2 NP_001034193.2 transient receptor potential cation channel subfamily M member 1 isoform 2
NM_018752.3 NP_061222.3 transient receptor potential cation channel subfamily M member 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables monoatomic cation channel activity IDA
IDA: Inferred from direct assay
19966281 MGI
enables monoatomic ion channel activity IMP
IMP: Inferred from mutant phenotype
36179691 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cellular response to light stimulus IMP
IMP: Inferred from mutant phenotype
19966281 MGI
involved in cellular response to light stimulus IMP
IMP: Inferred from mutant phenotype
19861548 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
31891182 MGI
acts upstream of or within retinal rod cell development IMP
IMP: Inferred from mutant phenotype
19966281 MGI
acts upstream of or within signal transduction IGI
IGI: Inferred from genetic interaction
19966281 MGI
Cellular Component GO Annotation Evidence References Source
is active in cell tip IDA
IDA: Inferred from direct assay
25997951 MGI
is active in dendrite IDA
IDA: Inferred from direct assay
25997951 MGI
located in new growing cell tip IDA
IDA: Inferred from direct assay
19966281 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transient receptor potential cation channel subfamily M member 1

  • long transient receptor potential channel 1

  • melastatin-1

Related Agents

  • Approval
  • Clinical Phase
  • Pre-clinical Phase

Approval

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0151 Pregnenolone 99.85% Unkown
HY-110189 Pregnenolone monosulfate sodium 99.96% Unkown
HY-B1739 Pregnenolone monosulfate 99.96% Unkown

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-B0151R Pregnenolone (Standard) 99.91% Phase 4

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-110220 CIM0216 Agonist 99.94% Unkown
HY-101464 ML329 Inhibitor 98.0% Unkown
HY-156483 TT-012 Inhibitor 99.76% Unkown
HY-B0151S2 Pregnenolone-d4-1 99.34% Unkown
HY-110189S1 Pregnenolone monosulfate-d4 sodium 99.8% Unkown
HY-B0151S Pregnenolone-d4 / Unkown
HY-B0151S1 Pregnenolone-13C2,d2 99.2% Unkown
HY-110189S Pregnenolone monosulfate sodium-13C2,d2 / Unkown
HY-B0151S3 Pregnenolone-d6 / Unkown
HY-RS15111 TRPM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17998 Trpm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24470 Trpm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpm1 NCBI NCBI:4308