Naca - nascent polypeptide-associated complex alpha polypeptide Gene

Also Known as skNAC; Gm1878; mKIAA0363

Species: Mus musculus

Gene Type: protein coding
Gene ID: 17938

Summary

Enables TBP-class protein binding activity and transcription coactivator activity. Involved in several processes, including heart development; negative regulation of striated muscle cell apoptotic process; and positive regulation of skeletal muscle tissue growth. Acts upstream of or within myoblast migration. Located in cytoplasm and nucleus. Is expressed in several structures, including aorta; genitourinary system; gut; liver; and spleen. Orthologous to human NACA (nascent polypeptide associated complex subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Naca Products (3)

mRNA Protein Name
NM_001113199.1 NP_001106670.1 nascent polypeptide-associated complex subunit alpha isoform a
NM_001282976.1 NP_001269905.1 nascent polypeptide-associated complex subunit alpha isoform b
NM_013608.3 NP_038636.2 nascent polypeptide-associated complex subunit alpha isoform b

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables TBP-class protein binding IDA
IDA: Inferred from direct assay
9488445 MGI
enables transcription coactivator activity IDA
IDA: Inferred from direct assay
9488445 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within myoblast migration IMP
IMP: Inferred from mutant phenotype
23662692 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
9488445 MGI
located in nucleus IDA
IDA: Inferred from direct assay
9488445 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nascent polypeptide-associated complex subunit alpha

  • alpha-NAC, muscle-specific form

  • alpha-NAC/1.9.2

  • nascent polypeptide-associated complex alpha subunit

  • nascent polypeptide-associated complex subunit alpha, muscle-specific form

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (11)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101044 PPADS tetrasodium 99.9% Unkown
HY-128678 ORM-10103 Inhibitor 99.43% Unkown
HY-15515R SEA0400 (Standard) Inhibitor 98.11% Unkown
HY-105402 T 162559 Inhibitor / Unkown
HY-160508 NCX1-IN-1 Inhibitor / Unkown
HY-164684 Dichlorobenzamil Inhibitor / Unkown
HY-RS08999 NACA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09000 NACA2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W710915 Aprindine hydrochloride-d10 / Unkown
HY-RS18956 Naca Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25446 Naca Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Naca NCBI NCBI:4666