Nnmt - nicotinamide N-methyltransferase Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18113

Summary

Enables nicotinamide N-methyltransferase activity. Involved in nicotinamide metabolic process; regulation of cellular biosynthetic process; and regulation of protein modification process. Acts upstream of or within methylation. Located in cytosol. Orthologous to human NNMT (nicotinamide N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Nnmt Products (8)

mRNA Protein Name
NM_001311062.2 NP_001297991.1 nicotinamide N-methyltransferase isoform 2
NM_001409262.1 NP_001396191.1 nicotinamide N-methyltransferase isoform 1
NM_001409263.1 NP_001396192.1 nicotinamide N-methyltransferase isoform 1
NM_001409264.1 NP_001396193.1 nicotinamide N-methyltransferase isoform 2
NM_001409265.1 NP_001396194.1 nicotinamide N-methyltransferase isoform 3
NM_001409266.1 NP_001396195.1 nicotinamide N-methyltransferase isoform 4
NM_001409267.1 NP_001396196.1 nicotinamide N-methyltransferase isoform 5
NM_010924.4 NP_035054.1 nicotinamide N-methyltransferase isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables nicotinamide N-methyltransferase activity IDA
IDA: Inferred from direct assay
8845860 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within methylation IDA
IDA: Inferred from direct assay
8845860 MGI
involved in nicotinamide metabolic process IDA
IDA: Inferred from direct assay
26168293 MGI
involved in positive regulation of gluconeogenesis IMP
IMP: Inferred from mutant phenotype
26168293 MGI
involved in positive regulation of protein deacetylation IMP
IMP: Inferred from mutant phenotype
26168293 MGI
Cellular Component GO Annotation Evidence Références Source
located in cytosol IDA
IDA: Inferred from direct assay
8845860 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

nicotinamide N-methyltransferase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-138993A NNMT-IN-6 hydrochloride Inhibitor 99.75% Unkown
HY-138993 NNMT-IN-6 Inhibitor / Unkown
HY-151500C JBSNF-000028 Inhibitor / Unkown
HY-186163 CC-410 Inhibitor / Unkown
HY-111367 MS2734 Inhibitor / Unkown
HY-W1006754 NNMT-IN-7 Inhibitor 98.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nnmt NCBI NCBI:4837