2. Gene
  3. P2rx4 - purinergic receptor P2X, ligand-gated ion channel 4 Gene

P2rx4 - purinergic receptor P2X, ligand-gated ion channel 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P2X4; D5Ertd444e

Gene ID: 18438 | Gene type: protein coding

About P2rx4

Chromosome 5: 122,845,607-122,867,801 forward strand.GRCm39:CM000998.3

This gene has 9 transcripts (splice variants), 211 orthologues, 6 paralogues and is associated with 13 phenotypes. Ubiquitous expression in colon adult (RPKM 57.8), lung adult (RPKM 28.) and 23 other tissues.

Summary

Enables extracellularly ATP-gated cation channel activity. Acts upstream of or within several processes, including excitatory postsynaptic potential; nitric oxide biosynthetic process; and vasodilation. Located in apical part of cell. Is expressed in several structures, including cardiovascular system; gut; immune system; nervous system; and viscerocranium. Orthologous to human P2RX4 (purinergic receptor P2X 4). [provided by Alliance of Genome Resources, Apr 2022]

P2rx4 Products(3)

mRNA Protein Name
NM_001310720.1 NP_001297649.1 P2X purinoceptor 4 isoform 3
NM_011026.3 NP_035156.2 P2X purinoceptor 4 isoform 1
NM_001310718.1 NP_001297647.1 P2X purinoceptor 4 isoform 2

P2rx4 Protein Structure

P2X_receptor

P2X_receptor: pfam00864 (12 - 360)

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  • 388 a.a.
Protein Preferred Names Protein Names

P2X purinoceptor 4

ionotropic purinergic receptor

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09906 P2RX4 Human Pre-designed siRNA Set A / Unkown
HY-RS09907 P2rx4 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09908 P2rx4 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx4 NCBI NCBI:5025