Pdcd6 - programmed cell death 6 Gene
Also Known as PS2; Alg2; MA-3; alg-2
Species: Mus musculus
Summary
Enables calcium-dependent protein binding activity; metal ion binding activity; and protein homodimerization activity. Involved in response to calcium ion. Acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process and apoptotic process. Located in cytoplasm. Orthologous to human PDCD6 (programmed cell death 6). [provided by Alliance of Genome Resources, Apr 2022]
Pdcd6 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001359996.1 | NP_001346925.1 | programmed cell death protein 6 isoform 2 |
| NM_011051.3 | NP_035181.1 | programmed cell death protein 6 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables calcium ion binding |
IMP
IMP: Inferred from mutant phenotype
|
17214967 | MGI |
| enables calcium-dependent protein binding |
IPI
IPI: Inferred from physical interaction
|
17214967 | MGI |
| enables magnesium ion binding |
IDA
IDA: Inferred from direct assay
|
27541325 | MGI |
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
11606059 | MGI |
| enables protein dimerization activity |
IPI
IPI: Inferred from physical interaction
|
10200558 | MGI |
| enables protein homodimerization activity |
IDA
IDA: Inferred from direct assay
|
27541325 | MGI |
| enables protein homodimerization activity |
IPI
IPI: Inferred from physical interaction
|
10200558 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within activation of cysteine-type endopeptidase activity involved in apoptotic process |
IDA
IDA: Inferred from direct assay
|
14561754 | MGI |
| acts upstream of or within apoptotic process |
IDA
IDA: Inferred from direct assay
|
8560270 | MGI |
| involved in response to calcium ion |
IDA
IDA: Inferred from direct assay
|
17214967 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in cytoplasm |
IDA
IDA: Inferred from direct assay
|
17214967 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
programmed cell death protein 6 |
|
|