Lcp1 - lymphocyte cytosolic protein 1 Gene

Also Known as Pls2; pp65; LCP-1; D14Ertd310e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 18826

Summary

Enables actin filament binding activity and identical protein binding activity. Acts upstream of or within actin filament bundle assembly. Located in several cellular components, including actin filament; phagocytic cup; and ruffle. Is expressed in several structures, including brain; cardiovascular system; egg cylinder; female reproductive system; and gut. Orthologous to human LCP1 (lymphocyte cytosolic protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Lcp1 Products (4)

mRNA Protein Name
NM_001247984.1 NP_001234913.1 plastin-2
NM_008879.4 NP_032905.2 plastin-2
NM_001247984.1 NP_001234913.1 plastin-2
NM_008879.4 NP_032905.2 plastin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables actin filament binding IDA
IDA: Inferred from direct assay
14756805 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
14756805 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within actin filament bundle assembly IDA
IDA: Inferred from direct assay
14756805 MGI
Cellular Component GO Annotation Evidence References Source
located in actin cytoskeleton IDA
IDA: Inferred from direct assay
7655078 MGI
located in actin filament IDA
IDA: Inferred from direct assay
14756805 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
14756805 MGI
located in glial cell projection IDA
IDA: Inferred from direct assay
14756805 MGI
located in phagocytic cup IDA
IDA: Inferred from direct assay
14756805 MGI
located in ruffle IDA
IDA: Inferred from direct assay
14756805 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

plastin-2

  • 65 kDa macrophage protein

  • L-fimbrin

  • L-plastin (Lymphocyte cytosolic protein 1) (LCP-1) (65 kDa macrophage protein) (PP65)

  • plastin 2, L

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07563 LCP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14911 TOX4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19347 Lcp1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25838 Lcp1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lcp1 NCBI NCBI:3936