Srgn - serglycin Gene

Also Known as Prg; Sgc; Prg1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19073

Summary

Predicted to enable Collagen binding activity. Involved in several processes, including protein localization to secretory granule; protein processing; and regulation of postsynapse organization. Located in several cellular components, including Schaffer collateral - CA1 synapse; mast cell granule; and postsynaptic specialization, intracellular component. Is expressed in several structures, including autopod; central nervous system; liver; lower jaw; and thymus primordium. Orthologous to human SRGN (serglycin). [provided by Alliance of Genome Resources, Apr 2022]

Srgn Products (2)

mRNA Protein Name
NM_001358965.1 NP_001345894.1 serglycin precursor
NM_011157.3 NP_035287.1 serglycin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
7535771 MGI
Biological Process GO Annotation Evidence References Source
involved in T cell secretory granule organization IMP
IMP: Inferred from mutant phenotype
16046402 MGI
involved in maintenance of granzyme B location in T cell secretory granule IMP
IMP: Inferred from mutant phenotype
16046402 MGI
involved in maintenance of protease location in mast cell secretory granule IMP
IMP: Inferred from mutant phenotype
17010166 MGI
involved in mast cell secretory granule organization IMP
IMP: Inferred from mutant phenotype
15231821 MGI
involved in negative regulation of cytokine production IMP
IMP: Inferred from mutant phenotype
16807245 MGI
involved in protein processing IDA
IDA: Inferred from direct assay
17081126 MGI
Cellular Component GO Annotation Evidence References Source
located in mast cell granule IDA
IDA: Inferred from direct assay
15231821 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serglycin

  • gp600

  • mastocytoma proteoglycan core protein

  • proteoglycan 1, secretory granule

  • proteoglycan, secretory granule

  • secretory granule proteoglycan core protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13766 SRGN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17592 Srgn Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24052 Srgn Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srgn NCBI NCBI:5552