Sftpd - surfactant associated protein D Gene

Also Known as SP-D; Sfpd; Sftp4

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20390

Summary

Enables identical protein binding activity. Predicted to be involved in several processes, including induction of Bacterial agglutination; negative regulation of interleukin-2 production; and regulation of phagocytosis. Predicted to act upstream of or within innate immune response and respiratory gaseous exchange by respiratory system. Located in cytoplasm. Is expressed in lung; otic capsule; and skeleton. Human ortholog(s) of this gene implicated in asthma; lung disease (multiple); respiratory syncytial virus infectious disease; and rhinitis. Orthologous to human SFTPD (surfactant protein D). [provided by Alliance of Genome Resources, Apr 2022]

Sftpd Products (1)

mRNA Protein Name
NM_009160.2 NP_033186.1 pulmonary surfactant-associated protein D precursor

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
19007302 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
21408140 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pulmonary surfactant-associated protein D

  • PSP-D

  • lung surfactant protein D

Sftpd Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Sftpd P50404 Sftpd Mus musculus P50404
GMS
19007302
Intra
Sftpd P50404 Sftpd Mus musculus P50404
Comig Non-Denat Gel
19007302
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant Sftpd Proteins

Cat. No. Product Name Accession Purity
HY-P71329 SP-D Protein, Mouse (HEK293, His) P50404 (A20-F374) ≥ 95%, as determined by reducing SDS-PAGE.

Sftpd Antibodies

Cat. No. Product Name Application Reactivity
HY-P82362 Pulmonary Surfactant Associated Protein D Antibody (YA2107) WB, IHC-P Rat
HY-P82362A Pulmonary Surfactant Associated Protein D Antibody (YA2107)(PBS only) WB, IHC-P Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12784 SFTPD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17774 Sftpd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24241 Sftpd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sftpd NCBI NCBI:6441