Slc7a5 - solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 Gene

Also Known as TA1; LAT1; 4F2LC; Gm42049; D0H16S474E

Species: Mus musculus

Gene Type: protein coding
Gene ID: 20539

Summary

Enables L-amino acid transmembrane transporter activity. Acts upstream of or within L-amino acid transport. Predicted to be located in several cellular components, including basolateral plasma membrane; external side of apical plasma membrane; and microvillus membrane. Predicted to be integral component of membrane. Predicted to be part of amino acid transport complex. Is expressed in several structures, including central nervous system; cochlea; early conceptus; incisor; and limb. Used to study autism spectrum disorder. Orthologous to human SLC7A5 (solute carrier family 7 member 5). [provided by Alliance of Genome Resources, Apr 2022]

Slc7a5 Products (1)

mRNA Protein Name
NM_011404.3 NP_035534.2 large neutral amino acids transporter small subunit 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
15659399 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
9915839 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within L-amino acid transport IDA
IDA: Inferred from direct assay
15659399 MGI
involved in L-leucine transport IDA
IDA: Inferred from direct assay
9915839 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
9915839 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

large neutral amino acids transporter small subunit 1

  • 4F2 LC

  • 4F2 light chain

  • L-type amino acid transporter 1

  • solute carrier family 7 member 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-120139 KMH-233 Inhibitor 99.75% Unkown
HY-133677 Mono(2-ethyl-5-hydroxyhexyl) phthalate 99.03% Unkown
HY-RS13331 SLC7A5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17279 Slc7a5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W267524 H-Phe(3-CF3)-OH / Unkown
HY-183513 L-Ala-BPA Substrate / Unkown
HY-158161 JN-170 Inhibitor / Unkown
HY-164401A QBS10072S dihydrochloride / Unkown
HY-RS23734 Slc7a5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-W772441 H-Phe(3-tBu)-OH hydrochloride / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc7a5 NCBI NCBI:8140