Bag2 - BCL2-associated athanogene 2 Gene

Also Known as 2610042A13Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 213539

Summary

Enables heat shock protein binding activity; Tau Protein binding activity; and ubiquitin protein Ligase binding activity. Involved in negative regulation of protein ubiquitination and positive regulation of proteasomal protein catabolic process. Located in axon and dendrite. Colocalizes with dendritic microtubule. Orthologous to human BAG2 (BAG cochaperone 2). [provided by Alliance of Genome Resources, Apr 2022]

Bag2 Products (1)

mRNA Protein Name
NM_145392.2 NP_663367.1 BAG family molecular chaperone regulator 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables heat shock protein binding IPI
IPI: Inferred from physical interaction
19228967 MGI
enables tau protein binding IPI
IPI: Inferred from physical interaction
19228967 MGI
Biological Process GO Annotation Evidence References Source
involved in negative regulation of protein ubiquitination IGI
IGI: Inferred from genetic interaction
19228967 MGI
involved in positive regulation of proteasomal protein catabolic process IGI
IGI: Inferred from genetic interaction
19228967 MGI
NOT involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process IGI
IGI: Inferred from genetic interaction
19228967 MGI
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
19228967 MGI
located in dendrite IDA
IDA: Inferred from direct assay
19228967 MGI
colocalizes with dendritic microtubule IDA
IDA: Inferred from direct assay
19228967 MGI
colocalizes with microtubule IDA
IDA: Inferred from direct assay
19228967 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BAG family molecular chaperone regulator 2

  • BAG-2

  • bcl-2-associated athanogene 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01343 BAG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18911 Bag2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25402 Bag2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bag2 NCBI NCBI:9532