Tbxas1 - thromboxane A synthase 1, platelet Gene

Also Known as TS; TXS; CYP5; THAS; TXAS; CYP5A1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21391

Summary

Enables thromboxane-A synthase activity. Predicted to be involved in cellular chloride ion homeostasis; positive regulation of vasoconstriction; and prostaglandin biosynthetic process. Predicted to act upstream of or within fatty acid biosynthetic process and prostaglandin metabolic process. Predicted to be located in endoplasmic reticulum membrane. Is expressed in several structures, including bone marrow; brain; liver; lung; and metanephros. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; and platelet-type bleeding disorder 14. Orthologous to human TBXAS1 (thromboxane A synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tbxas1 Products (4)

mRNA Protein Name
NM_001410475.1 NP_001397404.1 thromboxane-A synthase isoform 2
NM_001410476.1 NP_001397405.1 thromboxane-A synthase isoform 3
NM_001410477.1 NP_001397406.1 thromboxane-A synthase isoform 4
NM_011539.4 NP_035669.3 thromboxane-A synthase isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables thromboxane-A synthase activity IMP
IMP: Inferred from mutant phenotype
7688225 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thromboxane-A synthase

  • TXA synthase

  • cytochrome P450 5A1

  • hydroperoxy icosatetraenoate dehydratase

  • thromboxane synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14286 TBXAS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21954 Tbxas1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28471 Tbxas1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tbxas1 NCBI NCBI:6916