Tead3 - TEA domain family member 3 Gene

Also Known as TEF-5; DTEF-1; ETFR-1; TEAD-3; Tcf13r2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21678

Summary

This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and thought to play a role in placental gene regulation and development. Alternative splicing, and alternate use of an upstream AUG translation initiation codon, and an in-frame downstream non-AUG (AUA) codon, results in 2 isoforms. [provided by RefSeq, Jul 2008]

Tead3 Products (3)

mRNA Protein Name
NM_001098226.3 NP_001091696.2 transcriptional enhancer factor TEF-5 isoform 1
NM_001204156.1 NP_001191085.1 transcriptional enhancer factor TEF-5 isoform 2
NM_011566.4 NP_035696.3 transcriptional enhancer factor TEF-5 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
9502435 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of stem cell population maintenance IGI
IGI: Inferred from genetic interaction
20516196 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9502435 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
16207754 MGI
Cellular Component GO Annotation Evidence References Source
part of transcription regulator complex IGI
IGI: Inferred from genetic interaction
16207754 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional enhancer factor TEF-5

  • ETF-related factor 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-172113 H122 98.33% Phase 4

Pre-clinical Phase

Bioactive Molecules (20)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-134956 VT104 Inhibitor 99.94% Unkown
HY-147135 MYF-03-69 98.11% Unkown
HY-147136 MYF-03-176 Inhibitor 99.72% Unkown
HY-147208 MSC-4106 Inhibitor 99.87% Unkown
HY-163644 VT-105 Inhibitor 99.93% Unkown
HY-161569 TEAD-IN-11 Inhibitor 99.82% Unkown
HY-186117 KG-FP-003 Degrader / Unkown
HY-147209 DC-TEAD3in03 Inhibitor / Unkown
HY-161568 TEAD-IN-10 Inhibitor / Unkown
HY-170764 M3686 Inhibitor / Unkown
HY-173139 TEAD-IN-19 Inhibitor / Unkown
HY-181534 PROTAC TEAD1/IAP degrader-1 Degrader / Unkown
HY-182672 VT101 Inhibitor / Unkown
HY-183753 LC-TD-05 / Unkown
HY-184225 PROTAC TEAD degrader-3 Degrader / Unkown
HY-185230 HC278 Degrader / Unkown
HY-186118 TEAD ligand 6 Ligand / Unkown
HY-RS14344 TEAD3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18299 Tead3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24777 Tead3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tead3 NCBI NCBI:7005