Amph - amphiphysin Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 218038

Summary

Predicted to enable phospholipid binding activity and protein C-terminus binding activity. Involved in synaptic vesicle endocytosis. Acts upstream of or within learning. Located in synaptic vesicle. Is active in glutamatergic synapse; photoreceptor ribbon synapse; and presynaptic endocytic zone. Is expressed in several structures, including allantois; metanephros; pituitary gland; and septum transversum. Orthologous to human AMPH (amphiphysin). [provided by Alliance of Genome Resources, Apr 2022]

Amph Products (2)

mRNA Protein Name
NM_001289546.1 NP_001276475.1 amphiphysin isoform 2
NM_175007.2 NP_778172.1 amphiphysin isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12456676 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within learning IMP
IMP: Inferred from mutant phenotype
11879655 MGI
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
11879655 MGI
acts upstream of or within synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
11879655 MGI
involved in synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
11879655 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
11879655 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
11879655 MGI
is active in photoreceptor ribbon synapse IDA
IDA: Inferred from direct assay
23785143 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
11879655 MGI
is active in presynaptic endocytic zone IDA
IDA: Inferred from direct assay
23785143 MGI
located in synaptic vesicle IDA
IDA: Inferred from direct assay
11879655 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amphiphysin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-14327 FAUC 213 Antagonist 99.86% Unkown
HY-RS00669 AMPH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18227 Amph Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24705 Amph Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Amph NCBI NCBI:273
Macaca fascicularis Amph NCBI NCBI:102127478