Clec3b - C-type lectin domain family 3, member b Gene

Also Known as Tna

Species: Mus musculus

Gene Type: protein coding
Gene ID: 21922

Summary

Predicted to enable calcium ion binding activity; heparin binding activity; and kringle domain binding activity. Involved in positive regulation of plasminogen activation. Acts upstream of or within ossification and skeletal system development. Located in cytoplasm. Is expressed in several structures, including genitourinary system; gut; serum; skeletal musculature; and spinal cord. Used to study Scheuermann's disease. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human CLEC3B (C-type lectin domain family 3 member B). [provided by Alliance of Genome Resources, Apr 2022]

Clec3b Products (1)

mRNA Protein Name
NM_011606.2 NP_035736.2 tetranectin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12694198 MGI
Biological Process GO Annotation Evidence References Source
involved in ossification IEP
IEP: Inferred from expression pattern
7798325 MGI
involved in positive regulation of plasminogen activation IDA
IDA: Inferred from direct assay
12694198 MGI
acts upstream of or within skeletal system development IMP
IMP: Inferred from mutant phenotype
11604516 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15848710 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tetranectin

  • TN

  • plasminogen kringle 4-binding protein

  • tetranectin (plasminogen binding protein)

Recombinant Clec3b Proteins

Cat. No. Product Name Accession Purity
HY-P76671 Tetranectin/CLEC3B Protein, Mouse (HEK293, His) P43025 (E22-V202) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02790 CLEC3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18702 Clec3b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25189 Clec3b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clec3b NCBI NCBI:7123