GSTA5 - glutathione S-transferase alpha 5 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 221357

About GSTA5

Cytogenetic location: 6p12.2 Genomic coordinates (GRCh38): 6:52,831,692-52,846,245 (from NCBI)

This gene has 2 transcripts (splice variants), 133 orthologues and 11 paralogues. Low expression observed in reference dataset.

Summary

The glutathione S-transferases (GST; EC 2.5.1.18) catalyze the conjugation of reduced glutathiones and a variety of electrophiles, including many known carcinogens and mutagens. The cytosolic GSTs belong to a large superfamily, with members located on different chromosomes. For additional information on GSTs, see GSTA1 (MIM 138359).[supplied by OMIM, Sep 2008]

GSTA5 Products (1)

mRNA Protein Name
NM_153699.2 NP_714543.1 glutathione S-transferase A5

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GSTA5 Protein Structure

GST_N

GST_N: Glutathione S-transferase, N-terminal domain (6 - 76)

GST_C

GST_C: Glutathione S-transferase, C-terminal domain (102 - 192)

  • 0
  • 100
  • 200
  • 222 a.a.
Protein Preferred Names Protein Names

glutathione S-transferase A5

  • GST class-alpha member 5

GSTA5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
GSTA5 Q7RTV2 EIF3M Homo sapiens Q7L2H7
Anti Tag CoIP
33961781
Intra
GSTA5 Q7RTV2 TEX9 Homo sapiens Q8N6V9
Y2H Prey Pooling
32296183
Intra
GSTA5 Q7RTV2 TEX9 Homo sapiens Q8N6V9
Validated Y2H
32296183
Intra
GSTA5 Q7RTV2 TEX9 Homo sapiens Q8N6V9
Y2H Array
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05876 GSTA5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25930 Gsta1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GSTA5 RGD RGD:1593189
Others GSTA5 NCBI