Atf7 - activating transcription factor 7 Gene

Also Known as 1110012F10Rik; 9430065F09Rik; C130020M04Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 223922

Summary

Predicted to enable several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; cAMP response element binding activity; and transcription coactivator binding activity. Involved in several processes, including animal organ development; hepatocyte apoptotic process; and p38MAPK cascade. Predicted to be located in nucleoplasm. Is expressed in central nervous system; early conceptus; genitourinary system; and retina. Orthologous to human ATF7 (activating transcription factor 7). [provided by Alliance of Genome Resources, Apr 2022]

Atf7 Products (3)

mRNA Protein Name
NM_001310066.1 NP_001296995.1 cyclic AMP-dependent transcription factor ATF-7 isoform 1
NM_001310067.1 NP_001296996.1 cyclic AMP-dependent transcription factor ATF-7 isoform 1
NM_001310070.1 NP_001296999.1 cyclic AMP-dependent transcription factor ATF-7 isoform 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in heart development IGI
IGI: Inferred from genetic interaction
17699753 MGI
involved in hematopoietic progenitor cell differentiation IGI
IGI: Inferred from genetic interaction
17699753 MGI
involved in hepatocyte apoptotic process IGI
IGI: Inferred from genetic interaction
17699753 MGI
involved in in utero embryonic development IGI
IGI: Inferred from genetic interaction
17699753 MGI
involved in liver development IGI
IGI: Inferred from genetic interaction
17699753 MGI
involved in p38MAPK cascade IGI
IGI: Inferred from genetic interaction
17699753 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-dependent transcription factor ATF-7

  • cAMP-dependent transcription factor ATF-7

  • transcription factor ATF-A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS19118 Atf5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01136 ATF7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01137 ATF7IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20138 Atf7ip Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22108 Atf7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26641 Atf7ip Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28630 Atf7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atf7 NCBI NCBI:11016