Ythdf3 - YTH N6-methyladenosine RNA binding protein 3 Gene

Also Known as 9130022A11Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 229096

Summary

Predicted to enable N6-methyladenosine-containing RNA binding activity; mRNA binding activity; and ribosome binding activity. Involved in mRNA destabilization and negative regulation of type I interferon-mediated signaling pathway. Located in cytoplasm. Orthologous to human YTHDF3 (YTH N6-methyladenosine RNA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Ythdf3 Products (5)

mRNA Protein Name
NM_001145919.2 NP_001139391.1 YTH domain-containing family protein 3 isoform 2
NM_001358041.1 NP_001344970.1 YTH domain-containing family protein 3 isoform 3
NM_001358042.1 NP_001344971.1 YTH domain-containing family protein 3 isoform 4
NM_001358043.1 NP_001344972.1 YTH domain-containing family protein 3 isoform 4
NM_172677.4 NP_766265.3 YTH domain-containing family protein 3 isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in mRNA destabilization IMP
IMP: Inferred from mutant phenotype
32943573 MGI
involved in negative regulation of type I interferon-mediated signaling pathway IMP
IMP: Inferred from mutant phenotype
30591559 MGI
NOT involved in positive regulation of translational initiation IMP
IMP: Inferred from mutant phenotype
32943573 MGI
involved in regulation of mRNA stability IMP
IMP: Inferred from mutant phenotype
32943573 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
32943573 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

YTH domain-containing family protein 3

  • YTH domain family 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-176848 SKLB-Y13 Inhibitor 98.44% Unkown
HY-168610 YTH-IN-1 Inhibitor 98.66% Unkown
HY-RS15939 YTHDF3 Human Pre-designed siRNA Set A Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ythdf3 NCBI NCBI:253943