Plac8 - placenta-specific 8 Gene

Also Known as C15; D5Wsu111e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231507

Summary

Enables chromatin binding activity. Involved in positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Predicted to be located in nucleus. Is expressed in several structures, including extraembryonic component; gut; liver lobe; oculomotor nerve; and prostate gland lobe. Orthologous to human PLAC8 (placenta associated 8). [provided by Alliance of Genome Resources, Apr 2022]

Plac8 Products (2)

mRNA Protein Name
NM_001370754.1 NP_001357683.1 placenta-specific gene 8 protein
NM_139198.3 NP_631937.1 placenta-specific gene 8 protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
21982742 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16611984 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within brown fat cell differentiation IMP
IMP: Inferred from mutant phenotype
21982742 MGI
acts upstream of or within defense response to bacterium IMP
IMP: Inferred from mutant phenotype
17404296 MGI
acts upstream of or within negative regulation of apoptotic process IDA
IDA: Inferred from direct assay
12407160 MGI
acts upstream of or within negative regulation of apoptotic process IGI
IGI: Inferred from genetic interaction
12407160 MGI
acts upstream of or within negative regulation of multicellular organism growth IMP
IMP: Inferred from mutant phenotype
21982742 MGI
acts upstream of or within positive regulation of cell population proliferation IDA
IDA: Inferred from direct assay
16611984 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
21982742 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21982742 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21982742 MGI
acts upstream of or within response to cold IMP
IMP: Inferred from mutant phenotype
21982742 MGI
acts upstream of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
21982742 MGI
acts upstream of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21982742 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

placenta-specific gene 8 protein

  • onzin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10641 PLAC8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19731 Plac8 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26227 Plac8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plac8 NCBI NCBI:51316