2. Gene
  3. P2rx2 - purinergic receptor P2X, ligand-gated ion channel, 2 Gene

P2rx2 - purinergic receptor P2X, ligand-gated ion channel, 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P2x2; P2X2a

Gene ID: 231602 | Gene type: protein coding

About P2rx2

Chromosome 5: 110,487,678-110,491,078 reverse strand.GRCm39:CM000998.3

This gene has 6 transcripts (splice variants), 190 orthologues, 6 paralogues and is associated with 8 phenotypes. Biased expression in testis adult (RPKM 29.2), genital fat pad adult (RPKM 19.6) and 5 other tissues.

Summary

Enables extracellularly ATP-gated cation channel activity. Involved in sensory perception of sound. Acts upstream of or within several processes, including response to ATP; skeletal muscle fiber development; and smooth muscle contraction. Located in plasma membrane. Is expressed in facial ganglion; heart; medulla oblongata basal plate mantle layer; and vagus ganglion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 41. Orthologous to human P2RX2 (purinergic receptor P2X 2). [provided by Alliance of Genome Resources, Apr 2022]

P2rx2 Products(5)

mRNA Protein Name
NM_001164834.1 NP_001158306.1 P2X purinoceptor 2 isoform c
NM_001310700.1 NP_001297629.1 P2X purinoceptor 2 isoform d
NM_001164833.1 NP_001158305.1 P2X purinoceptor 2 isoform b
NM_153400.4 NP_700449.2 P2X purinoceptor 2 isoform a
NM_001310701.1 NP_001297630.1 P2X purinoceptor 2 isoform e

P2rx2 Protein Structure

P2X

P2X: TIGR00863 (13 - 379)

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  • 485 a.a.
Protein Preferred Names Protein Names

P2X purinoceptor 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09900 P2RX2 Human Pre-designed siRNA Set A / Unkown
HY-RS09901 P2rx2 Mouse Pre-designed siRNA Set A / Unkown
HY-RS09902 P2rx2 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens P2rx2 NCBI NCBI:22953