2. Gene
  3. FPR3 - formyl peptide receptor 3 Gene

FPR3 - formyl peptide receptor 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; FMLP-R-II; FML2_HUMAN

Gene ID: 2359 | Gene type: protein coding

About FPR3

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,795,157-51,826,190 (from NCBI)

This gene has 2 transcripts (splice variants), 76 orthologues and 8 paralogues. Broad expression in appendix (RPKM 15.7), gall bladder (RPKM 12.8) and 22 other tissues.

Summary

Predicted to enable N-formyl peptide receptor activity and Complement Receptor activity. Predicted to be involved in several processes, including Complement Receptor mediated signaling pathway; Phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FPR3 Products(1)

mRNA Protein Name
NM_002030.5 NP_002021.3 N-formyl peptide receptor 3

FPR3 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (43 - 302)

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  • 353 a.a.
Protein Preferred Names Protein Names

N-formyl peptide receptor 3

FMLP-related receptor II

Related Diseases

Diseases Alias
Anaerobic Meningitis
Rubeosis Iridis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-RS05087 FPR3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FPR3 MGD MGI:1194495
Rattus norvegicus FPR3 RGD RGD:1566044