FPR3 - formyl peptide receptor 3 Gene

Also Known as FMLPY; FPRH1; FPRH2; FPRL2; RMLP-R-I; FMLP-R-II; FML2_HUMAN

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 2359

About FPR3

Cytogenetic location: 19q13.41 Genomic coordinates (GRCh38): 19:51,795,157-51,826,190 (from NCBI)

This gene has 2 transcripts (splice variants), 76 orthologues and 8 paralogues. Broad expression in appendix (RPKM 15.7), gall bladder (RPKM 12.8) and 22 other tissues.

Summary

Predicted to enable N-formyl peptide receptor activity and Complement Receptor activity. Predicted to be involved in several processes, including Complement Receptor mediated signaling pathway; Phospholipase C-activating G protein-coupled receptor signaling pathway; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

FPR3 Products (1)

mRNA Protein Name
NM_002030.5 NP_002021.3 N-formyl peptide receptor 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15465011 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FPR3 Protein Structure

7tm_1

7tm_1: 7 transmembrane receptor (rhodopsin family) (43 - 302)

  • 0
  • 100
  • 200
  • 300
  • 353 a.a.
Protein Preferred Names Protein Names

N-formyl peptide receptor 3

  • FMLP-related receptor II

FPR3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P84208 FPR3 Antibody (YA3905) IHC-P, FC, ELISA Human
HY-P84208A FPR3 Antibody (YA3905)(PBS only) IHC-P, FC, ELISA Human

Related Diseases

Diseases Alias
Anaerobic Meningitis
Rubeosis Iridis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-116216 PD 168368 Antagonist ≥99.0% Unkown
HY-P11704 f-MKKFRW Activator / Unkown
HY-RS05087 FPR3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-184442 GPR132 antagonist-2 Antagonist / Unkown
HY-RS17805 Fpr3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24273 Fpr3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus FPR3 MGD MGI:1194495
Rattus norvegicus FPR3 RGD RGD:1566044
Others FPR3 NCBI