Ets2 - E26 avian leukemia oncogene 2, 3' domain Gene
Also Known as Ets-2
Species: Mus musculus
Summary
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within ectodermal cell fate commitment; mesoderm development; and primitive streak formation. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; sensory organ; and skeleton. Orthologous to human ETS2 (ETS proto-oncogene 2, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]
Ets2 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_011809.3 | NP_035939.3 | protein C-ets-2 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables RNA polymerase II transcription regulatory region sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
20176728 | MGI |
| enables sequence-specific DNA binding |
IDA
IDA: Inferred from direct assay
|
1409581 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within ectodermal cell fate commitment |
IGI
IGI: Inferred from genetic interaction
|
25446535 | MGI |
| acts upstream of or within mesoderm development |
IMP
IMP: Inferred from mutant phenotype
|
23552073 | MGI |
| acts upstream of or within primitive streak formation |
IMP
IMP: Inferred from mutant phenotype
|
23552073 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
protein C-ets-2 |
|