Abcc4 - ATP-binding cassette, sub-family C (CFTR/MRP), member 4 Gene

Also Known as MRP4; MOATB; ABCC4-N1; D630049P08Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 239273

Summary

Predicted to enable several functions, including ABC-type transporter activity; glutathione transmembrane transporter activity; and prostaglandin transmembrane transporter activity. Predicted to be involved in export across plasma membrane and organic anion transport. Predicted to act upstream of or within cilium assembly and prostaglandin secretion. Located in apical plasma membrane and basolateral plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ABCC4 (ATP binding cassette subfamily C member 4). [provided by Alliance of Genome Resources, Apr 2022]

Abcc4 Products (3)

mRNA Protein Name
NM_001033336.3 NP_001028508.2 ATP-binding cassette sub-family C member 4 isoform 1
NM_001163675.1 NP_001157147.1 ATP-binding cassette sub-family C member 4 isoform 2
NM_001163676.1 NP_001157148.1 ATP-binding cassette sub-family C member 4 isoform 3

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15314169 MGI
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
15314169 MGI
NOT located in cilium IDA
IDA: Inferred from direct assay
25173977 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
25173977 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-binding cassette sub-family C member 4

multidrug resistance-associated protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19989A MK-571 sodium 99.75% Unkown
HY-129764 Prostaglandin F3α Substrate / Unkown
HY-RS00063 ABCC4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20355 Abcc4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26864 Abcc4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Abcc4 NCBI NCBI:10257