GSPT1 - Gspt1 G1 to S phase transition 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24420

Summary

Predicted to enable GTPase activity and translation release factor activity. Predicted to be involved in cytoplasmic translational termination and regulation of translational termination. Predicted to act upstream of or within protein methylation. Predicted to be located in cytosol. Predicted to be part of translation release factor complex. Orthologous to human GSPT1 (G1 to S phase transition 1). [provided by Alliance of Genome Resources, Apr 2022]

GSPT1 Products (1)

mRNA Protein Name
NM_001003978.1 NP_001003978.1 eukaryotic peptide chain release factor GTP-binding subunit ERF3A
Protein Preferred Names Protein Names

eukaryotic peptide chain release factor GTP-binding subunit ERF3A

  • G1 to S phase transition protein 1

  • G1 to phase transition 1

  • eukaryotic peptide chain release factor GTP-binding subunit ERF3B-like

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-153356 MRT-2359 Inducer 99.98% Phase 2
HY-130800 Eragidomide 99.93% Phase 1
HY-164202 ORM-5029 96.53% Phase 1
HY-171792 BMS-986497 Inhibitor / Phase 1

Pre-clinical Phase

Bioactive Molecules (82)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101488 CC-885 99.26% Unkown
HY-132199 SJ6986 Degrader 98.35% Unkown
HY-145448 MC-VC-PABC-amide-PEG1-CH2-CC-885 99.93% Unkown
HY-W1135319 SB-405483 99.33% Unkown
HY-148837 GT19630 98.85% Unkown
HY-145696 SJ10542 Degrader 99.32% Unkown
HY-151902 SJ988497 Degrader 99.03% Unkown
HY-176444 CDK2 degrader 6 Degrader 99.81% Unkown
HY-150259 MDEG-541 Degrader 98.68% Unkown
HY-153803 GBD-9 Degrader 99.91% Unkown
HY-147158 ZXH-1-161 98.43% Unkown
HY-130122 MG-277 Inducer 98.68% Unkown
HY-170952 LYG-409 Degrader 98.11% Unkown
HY-156641 Sontigidomide Degrader 98.62% Unkown
HY-76719 (Z)-Sunitinib carboxylic acid Ligand ≥98.0% Unkown
HY-150616 SJPYT-195 Inhibitor 98.07% Unkown
HY-161101 MG degrader 1 Degrader 99.30% Unkown
HY-115728 PROTAC CDK9 degrader-4 99.65% Unkown
HY-168936 DP-15 99.06% Unkown
HY-172770 KMG-1068 99.73% Unkown
HY-W998347 ABS-752 hydrochloride 98.81% Unkown
HY-137340 WH-10417-099 Degrader 98.14% Unkown
HY-161696 AN5777 Inducer 98.37% Unkown
HY-170820 XYD049 Inhibitor 99.46% Unkown
HY-175453 MRT-23227 99.45% Unkown
HY-177761 GSPT1 degrader-15 95.05% Unkown
HY-RS05868 GSPT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-132862 ZXH-4-137 / Unkown
HY-143435 AG6033 Inducer / Unkown
HY-155552 GSPT1 degrader-1 / Unkown
HY-156747 GSPT1 degrader-2 / Unkown
HY-159609 GSPT1 degrader-9 / Unkown
HY-159610 GSPT1 degrader-10 / Unkown
HY-159619 Boc-azetidine-2C-oxotetrahydropyrimidin-bromophenyl / Unkown
HY-159620 Thalidomide 5-azetidine-2C-oxotetrahydropyrimidin-bromophenyl / Unkown
HY-159622 Boc-Pip-C-oxotetrahydropyrimidin-bromophenyl / Unkown
HY-159623 Thalidomide 5-Pip-C-oxotetrahydropyrimidin-bromophenyl / Unkown
HY-162533 GSPT1 degrader-4 Degrader / Unkown
HY-162534 GSPT1 degrader-5 Degrader / Unkown
HY-162535 GSPT1 degrader-6 Inhibitor / Unkown
HY-163938A PROTAC erf3a Degrader-2 / Unkown
HY-164340 Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP / Unkown
HY-170405 YB-3–17 Inhibitor / Unkown
HY-170407 mTOR/GSPT1 ligand-1 Ligand / Unkown
HY-173125 FDU73 Degrader / Unkown
HY-173386 HDAC6 ligand-4 Inhibitor / Unkown
HY-174238 GSPT1 degrader-7 / Unkown
HY-174266 WB156 Degrader / Unkown
HY-174428 PROTAC JAK2 degrader-1 / Unkown
HY-175040 PROTAC FLT-3 degrader 5 Degrader / Unkown
HY-175283 ABT-002 Degrader / Unkown
HY-175334 DHC-286 98.00% Unkown
HY-175810 GSPT1 degrader-8 Degrader / Unkown
HY-176128 BWA-6047 / Unkown
HY-177724 GSPT1 degrader-11 Degrader / Unkown
HY-177744 GSPT2 degrader-1 / Unkown
HY-177750 TD-522 Inducer / Unkown
HY-177751 GSPT1 degrader-12 / Unkown
HY-177752 GSPT1 degrader-13 / Unkown
HY-177753 GSPT1 degrader-14 / Unkown
HY-177758 PROTAC HDAC6 degrader 8 Degrader / Unkown
HY-177765 GSPT1 degrader-16 / Unkown
HY-177766 GSPT1 degrader-17 Inducer / Unkown
HY-179499 PROTAC EZH2 Degrader-9 / Unkown
HY-180836 DIX-01 / Unkown
HY-181084 PROTAC BCL6/GSPT1 Degrader-1 / Unkown
HY-181620 CDK2 degrader 9 Degrader / Unkown
HY-182623 WB214 Degrader / Unkown
HY-182807 CRBN ligand-899 / Unkown
HY-182813 MC-amide-C2-amide-(β-D-GlcUA)-amide-PEG1-CH2-CC-885 / Unkown
HY-184097 MS9117 / Unkown
HY-184248 FM-74-103 Inhibitor / Unkown
HY-184896 XYD113 Inhibitor / Unkown
HY-187168 KAT2A degrader-1 Degrader / Unkown
HY-187337 HaloPROTAC 4 / Unkown
HY-187338 CRBN ligand-908 / Unkown
HY-188006 GSPT1 degrader-18 / Unkown
HY-W1128213 IKZF2-degrader 2 Degrader / Unkown
HY-W599025 5-Br-4-Cl-Pyrrolo-pyroxypyridine / Unkown
HY-W599279 ABS-752 Degrader / Unkown
HY-RS16544 Gspt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22976 Gspt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P9S0124 Anti-CD33 Antibody (OR000283) 99.00% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens GSPT1 NCBI NCBI:2935