ABT-002
ABT-002 is a molecular glue degrader targeting GSPT1 and NEK7. ABT-002 is the active metabolite of ABS-752 (HY-W599279). ABT-002 is promising for research of hepatocellular carcinoma (HCC).
For research use only. We do not sell to patients.
- CAS No.: 2438239-83-7
- Formula: C14H11FN2O5
- Molecular Weight:306.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Eukaryotic Release Factor (eRF) Isoforms
More
Biological Activity
Description
IC50 & Target
[1]|
NEK7 |
eRF3a/GSPT1 |
Chemical Information
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CAS No. 2438239-83-7
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Molecular Weight 306.25
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Formula C14H11FN2O5
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SMILES
O=C1CCC(C(N1)=O)N2CC3=C(C2=O)C=C(C(C(O)=O)=C3)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Liver Cancer Modeling
Liver cancer can be classified into primary liver cancer and secondary liver cancer. Secondary liver cancer is the metastatic liver cancer. Primary liver cancer includes hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (ICC) and fibrolamellar HCC, of which HCC is the most common form, accounting for approximately 90% of primary liver cancers[1]. HCC mouse models include chemical agent-induced models, transplanted tumor models, and genetic engineered models.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ABT-002 Related Classifications
HY-175283 Related Classifications
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