HDAC6 ligand-4
HDAC6 ligand-4 is a targeted ligand for histone deacetylase 6 (HDAC6). HDAC6 ligand-4 can serve as a target protein ligand for TO-1187 (HY-173266) and is used in studies related to PROTAC synthesis.
For research use only. We do not sell to patients.
- Formula: C17H17N3O2
- Molecular Weight:295.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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HDAC6 |
HDAC6 ligand-4 acts as a target protein ligand for TO-1187 (HY-173266), a selective HDAC6 PROTAC degrader (DC50 = 5.81 nM). TO-1187 promotes the ubiquitination and degradation of HDAC6[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 295.34
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Formula C17H17N3O2
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SMILES
O=C(C1=CC=C(C=C1)CN(CC2=CN=CC=C2)CC#C)NO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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