Me1 - malic enzyme 1 Gene

Also Known as MOD1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24552

Summary

Enables NADP binding activity and malate dehydrogenase (decarboxylating) (NADP+) activity. Involved in response to hormone. Located in cytosol and mitochondrion. Orthologous to human ME1 (malic enzyme 1). [provided by Alliance of Genome Resources, Apr 2022]

Me1 Products (1)

mRNA Protein Name
NM_012600.3 NP_036732.3 NADP-dependent malic enzyme

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables NADP binding IDA
IDA: Inferred from direct assay
17447164 RGD
enables malate dehydrogenase (decarboxylating) (NADP+) activity IDA
IDA: Inferred from direct assay
2416344 RGD
enables malic enzyme activity IDA
IDA: Inferred from direct assay
11735100 RGD
Biological Process GO Annotation Evidence References Source
involved in response to hormone IDA
IDA: Inferred from direct assay
2416344 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
2416344 RGD
located in mitochondrion IDA
IDA: Inferred from direct assay
9681477 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NADP-dependent malic enzyme

  • NADP-ME

  • cytosolic malic enzyme 1

  • malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)

  • malic enzyme 1, NADP(+)-dependent, cytosolic

  • malic enzyme 1, soluble

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P99595 Sirtratumab vedotin 97.38% Phase 1
HY-172661 Kylo-0603 / Phase 1

Pre-clinical Phase

Bioactive Molecules (29)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-15227 EPZ004777 99.74% Unkown
HY-124861 Malic enzyme inhibitor ME1 Inhibitor 99.69% Unkown
HY-403538 iZMYND8-34 Inhibitor 98.89% Unkown
HY-150621 AS1134900 Activator 98.87% Unkown
HY-15227A EPZ004777 hydrochloride 98.92% Unkown
HY-149677 ZK53 99.19% Unkown
HY-149091 KDM5B-IN-4 Inhibitor 99.68% Unkown
HY-128912 Arborinine Inhibitor 99.87% Unkown
HY-149213 LSD1/TLK1-IN-1 99.20% Unkown
HY-P2254 H3K27(Me3) (15-34) 96.97% Unkown
HY-P2255 H3K4(Me) (1-20) 99.87% Unkown
HY-RS08270 ME1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-115619 EPZ004777 formate / Unkown
HY-124961 LSD1-IN-2 Inhibitor / Unkown
HY-158436 Antitumor agent-155 / Unkown
HY-164144 EPZ033294 Inhibitor 98.41% Unkown
HY-168086 LSD1-IN-35 Inhibitor / Unkown
HY-174450 KMT9-IN-1 Inhibitor / Unkown
HY-176283 Tubulin/LSD1-IN-1 / Unkown
HY-181781 LSD1-IN-48 / Unkown
HY-181849 MS2928 Inhibitor / Unkown
HY-182054 Topoisomerase ll/ME-1-IN-1 / Unkown
HY-P10819 S9-CMC1 TFA / Unkown
HY-P2252 H3K27(Me) (15-34) / Unkown
HY-P2253 H3K27(Me2) (15-34) / Unkown
HY-RS10137 PCDHB16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17185 Me1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21063 Tcf12 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23636 Me1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991080 Anti-SLC44A4 Antibody ≥99.0% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Me1 NCBI NCBI:4199
Mus musculus Me1 NCBI NCBI:17436