2. Peptides
  3. H3K27(Me3) (15-34)

H3K27(Me3) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me).

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H3K27(Me3) (15-34) Chemical Structure

H3K27(Me3) (15-34) Chemical Structure

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1 mg USD 220 In-stock
5 mg USD 550 In-stock
10 mg USD 850 In-stock
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Based on 1 publication(s) in Google Scholar

H3K27(Me3) (15-34) Related Antibodies

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Description

H3K27(Me3) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me)[1][2].

Molecular Weight

2023.40

Formula

C87H157N30O25
Appearance

Solid

Color

White to off-white

Sequence

Ala-Pro-Arg-Lys-Gln-Leu-Ala-Thr-Lys-Ala-Ala-Arg-{Lys(Me3)}-Ser-Ala-Pro-Ala-Thr-Gly-Gly
Sequence Shortening

APRKQLATKAAR-{Lys(Me3)}-SAPATGG
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : ≥ 50 mg/mL (24.71 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4942 mL 2.4711 mL 4.9422 mL
5 mM 0.0988 mL 0.4942 mL 0.9884 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.4942 mL 2.4711 mL 4.9422 mL 12.3554 mL
5 mM 0.0988 mL 0.4942 mL 0.9884 mL 2.4711 mL
10 mM 0.0494 mL 0.2471 mL 0.4942 mL 1.2355 mL
15 mM 0.0329 mL 0.1647 mL 0.3295 mL 0.8237 mL
20 mM 0.0247 mL 0.1236 mL 0.2471 mL 0.6178 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

H3K27(Me3) (15-34)OthersPRC2histonepeptiderepressivemethyltransferasedemethylase， di-methylationEZHchromodomainproteinPRC1Inhibitorinhibitorinhibit

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