Rbbp7 - retinoblastoma binding protein 7, chromatin remodeling factor Gene

Also Known as mRbAp46

Species: Mus musculus

Gene Type: protein coding
Gene ID: 245688

Summary

Enables RNA binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of ESC/E(Z) complex and NuRD complex. Is expressed in several structures, including alimentary system; brain; early embryo; genitourinary system; and hemolymphoid system. Orthologous to human RBBP7 (RB binding protein 7, chromatin remodeling factor). [provided by Alliance of Genome Resources, Apr 2022]

Rbbp7 Products (1)

mRNA Protein Name
NM_009031.3 NP_033057.3 histone-binding protein RBBP7

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables RNA binding IPI
IPI: Inferred from physical interaction
22911650 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11836251 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12376095 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12376095 MGI
Cellular Component GO Annotation Evidence References Source
part of ESC/E(Z) complex IDA
IDA: Inferred from direct assay
31451685 MGI
part of NuRD complex IDA
IDA: Inferred from direct assay
14645126 MGI
located in nucleus IDA
IDA: Inferred from direct assay
12376095 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone-binding protein RBBP7

  • G1/S transition control protein-binding protein

  • RBBP-7

  • histone acetyltransferase type B subunit 2

  • nucleosome-remodeling factor subunit RBAP46

  • retinoblastoma-binding protein 7

  • retinoblastoma-binding protein p46

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11719 RBBP7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21723 Rbbp7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28241 Rbbp7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rbbp7 NCBI NCBI:5931