Mx1 - MX dynamin like GTPase 1 Gene

Also Known as IFI78

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24575

Summary

Predicted to enable GTPase activity; identical protein binding activity; and microtubule binding activity. Involved in response to virus. Located in nucleus. Human ortholog(s) of this gene implicated in alopecia areata; avian influenza; liver disease; and prostate Cancer. Orthologous to human MX1 (MX Dynamin like GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]

Mx1 Products (6)

mRNA Protein Name
NM_001271058.1 NP_001257987.1 interferon-induced GTP-binding protein Mx1
NM_001271059.1 NP_001257988.1 interferon-induced GTP-binding protein Mx1
NM_001271060.1 NP_001257989.1 interferon-induced GTP-binding protein Mx1
NM_001271061.1 NP_001257990.1 interferon-induced GTP-binding protein Mx1
NM_001271062.1 NP_001257991.1 interferon-induced GTP-binding protein Mx1
NM_173096.3 NP_775119.2 interferon-induced GTP-binding protein Mx1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in response to virus IDA
IDA: Inferred from direct assay
2173790 RGD
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
2173790 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interferon-induced GTP-binding protein Mx1

  • Myxovirus (influenza) resistance, homolog of murine Mx (also interferon-inducible protein IFI78)

  • myxoma resistance protein 1

  • myxovirus (influenza virus) resistance 1

  • myxovirus resistance protein 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Phase
HY-106031 F-14512 Inhibitor 98.04% Phase 2
HY-12098 Verubulin hydrochloride Inhibitor 98.71% Phase 2
HY-106401 Penclomedine / Phase 1

Pre-clinical Phase

Bioactive Molecules (13)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-160229 ssRNA40 sodium 98.34% Unkown
HY-N0167 Gynostemma Extract Inhibitor 99.92% Unkown
HY-123805 KIN1400 98.1% Unkown
HY-10615 A-620223 Inhibitor 98.84% Unkown
HY-162465 BDW568 Agonist 99.4% Unkown
HY-RS18454 Mx1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-106031A F-14512 hydrochloride Inhibitor / Unkown
HY-131438 GI-149893 Inhibitor / Unkown
HY-14687 (rac)-Talazoparib Inhibitor / Unkown
HY-181796 TLR7 antagonist-1 / Unkown
HY-RS08859 MX1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-121372 Lactandrate / Unkown
HY-RS24935 Mx1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mx1 NCBI NCBI:4599