Ppbp - pro-platelet basic protein Gene

Also Known as Cxcl7; Nap-2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246358

Summary

Predicted to enable CXCR Chemokine Receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; chemokine-mediated signaling pathway; and neutrophil chemotaxis. Predicted to act upstream of or within leukocyte migration involved in inflammatory response. Predicted to be located in platelet alpha granule. Predicted to be active in extracellular space. Orthologous to human PPBP (pro-platelet basic protein). [provided by Alliance of Genome Resources, Apr 2022]

Ppbp Products (1)

mRNA Protein Name
NM_153721.1 NP_714943.1 platelet basic protein precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of granulocyte chemotaxis IDA
IDA: Inferred from direct assay
15016410 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet basic protein

  • chemokine (C-X-C motif) ligand 7

  • neutrophil activating peptide-2

Recombinant Ppbp Proteins

Cat. No. Product Name Accession Purity
HY-P7269 NAP-2/CXCL7 Protein, Rat Q99ME0 (I46-I107) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P7301 NAP-2/CXCL7 Protein, Rat (CHO) Q99ME0 (I46-I107) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75699 NAP-2/CXCL7 Protein, Rat (HEK293, Fc) Q99ME0 (I46-I107) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P75700 NAP-2/CXCL7 Protein, Rat (P.pastoris, His) Q99ME0 (K38-Y111) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101043 4-PPBP maleate 99.63% Unkown
HY-RS10933 PPBP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17038 Ppbp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23482 Ppbp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppbp NCBI NCBI:5473