Stat5a - signal transducer and activator of transcription 5A Gene

Also Known as Stat5

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24918

Summary

Enables DNA-binding transcription factor activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; receptor signaling pathway via JAK-STAT; and response to ethanol. Acts upstream of or within cellular response to cytokine stimulus and cellular response to organic cyclic compound. Located in cytoplasm and nucleus. Orthologous to human STAT5A (signal transducer and activator of transcription 5A). [provided by Alliance of Genome Resources, Apr 2022]

Stat5a Products (1)

mRNA Protein Name
NM_017064.2 NP_058760.2 signal transducer and activator of transcription 5A

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
11064147 RGD
enables double-stranded DNA binding IDA
IDA: Inferred from direct assay
8584036 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
10713133 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
11064147 RGD
Biological Process GO Annotation Evidence References Source
involved in cell surface receptor signaling pathway via JAK-STAT IDA
IDA: Inferred from direct assay
11064147 RGD
acts upstream of or within cellular response to cytokine stimulus IDA
IDA: Inferred from direct assay
19414010 RGD
acts upstream of or within cellular response to organic cyclic compound IDA
IDA: Inferred from direct assay
19414010 RGD
involved in lactation IEP
IEP: Inferred from expression pattern
7519723 RGD
involved in mammary gland involution IDA
IDA: Inferred from direct assay
16227201 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
16946407 RGD
involved in response to nutrient levels IEP
IEP: Inferred from expression pattern
16946407 RGD
involved in transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
11064147 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

signal transducer and activator of transcription 5A

  • mammary gland factor

  • signal transducer and activator of transcription 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (16)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-126675A AS2863619 98.02% Unkown
HY-148813 AK-2292 99.73% Unkown
HY-169182 AK-068 Ligand 99.57% Unkown
HY-136546 Stafia-1 Inhibitor 99.39% Unkown
HY-19527 IST5-002 99.83% Unkown
HY-126675 AS2863619 free base 99.87% Unkown
HY-112648 Stafib-2 Inhibitor 99.97% Unkown
HY-115464 NC1153 / Unkown
HY-126675G AS2863619 (GMP) / Unkown
HY-170837 STAT5-IN-3 Inhibitor / Unkown
HY-182430 NVP-BVB808 / Unkown
HY-184991 AK305 Ligand / Unkown
HY-RS13892 STAT5A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N19899 Phaeosphaeride A / Unkown
HY-RS19077 Stat5a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25568 Stat5a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stat5a NCBI NCBI:6776