Scp2 - sterol carrier protein 2 Gene

Also Known as SCPx; NSLIPTR

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25541

Summary

Enables C-acyltransferase activity; identical protein binding activity; and lipid transfer activity. Involved in several processes, including cellular response to cholesterol; monocarboxylic acid metabolic process; and positive regulation of Cholesterol biosynthetic process. Located in several cellular components, including endoplasmic reticulum; mitochondrion; and peroxisomal matrix. Is extrinsic component of mitochondrial outer membrane. Orthologous to human SCP2 (sterol carrier protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Scp2 Products (1)

mRNA Protein Name
NM_138508.5 NP_612517.3 sterol carrier protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables acetyl-CoA C-acyltransferase activity IDA
IDA: Inferred from direct assay
8063752 RGD
enables acetyl-CoA C-myristoyltransferase activity IDA
IDA: Inferred from direct assay
9325339 RGD
enables cholesterol transfer activity IDA
IDA: Inferred from direct assay
8063752 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
10733876 RGD
enables phosphatidylcholine transfer activity IDA
IDA: Inferred from direct assay
8063752 RGD
enables phosphatidylethanolamine transfer activity IDA
IDA: Inferred from direct assay
8606365 RGD
enables propionyl-CoA C2-trimethyltridecanoyltransferase activity IDA
IDA: Inferred from direct assay
9245689 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
10733876 RGD
Biological Process GO Annotation Evidence References Source
involved in bile acid metabolic process IDA
IDA: Inferred from direct assay
9325339 RGD
involved in cellular response to cholesterol IEP
IEP: Inferred from expression pattern
7989577 RGD
involved in fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
9325339 RGD
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
16772292 RGD
involved in positive regulation of cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
2554812 RGD
involved in positive regulation of cholesterol import IDA
IDA: Inferred from direct assay
16772292 RGD
involved in positive regulation of steroid biosynthetic process IDA
IDA: Inferred from direct assay
1703300 RGD
involved in positive regulation of steroid biosynthetic process IMP
IMP: Inferred from mutant phenotype
3030719 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
2474437 RGD
involved in response to luteinizing hormone IEP
IEP: Inferred from expression pattern
2249635 RGD
Cellular Component GO Annotation Evidence References Source
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
8063752 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
9325339 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sterol carrier protein 2

  • NSL-TP

  • SCP-2

  • SCP-2/3-oxoacyl-CoA thiolase

  • SCP-2/thiolase

  • SCP-X

  • SCP-chi

  • Sterol carrier protein 2, liver

  • acetyl-CoA C-myristoyltransferase

  • non-specific lipid-transfer protein

  • propanoyl-CoA C-acyltransferase

  • sterol carrier protein X

  • straight-chain

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-124824 Methyl gerfelin Inhibitor 99.9% Unkown
HY-N15885 12-NBD Stearate Ligand / Unkown
HY-RS03292 CTDSP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12559 SCP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14071 SYCP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-180460 SCPI-1 / Unkown
HY-180500 SCPI-3 / Unkown
HY-RS20817 Scp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27331 Scp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Scp2 NCBI NCBI:6342