Il7 - interleukin 7 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25647

Summary

Predicted to enable cytokine activity and growth factor activity. Involved in cellular response to hypoxia and response to X-ray. Predicted to be located in extracellular space. Used to study high grade glioma. Biomarker of periodontal disease. Human ortholog(s) of this gene implicated in epidermodysplasia verruciformis. Orthologous to human IL7 (interleukin 7). [provided by Alliance of Genome Resources, Apr 2022]

Il7 Products (1)

mRNA Protein Name
NM_013110.3 NP_037242.2 interleukin-7 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to hypoxia IEP
IEP: Inferred from expression pattern
19055876 RGD
involved in response to X-ray IEP
IEP: Inferred from expression pattern
15799696 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-7

  • IL-7

Recombinant Il7 Proteins

Cat. No. Product Name Accession Purity
HY-P73227 IL-7 Protein, Rat Q91Y32 (D26-I154) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (5)
Cat. No. Product Name Effect
Purity Phase
HY-P99412 Lusvertikimab Antagonist 99.41% Phase 2
HY-P990023 Bempikibart Antagonist 98.00% Phase 2
HY-P99908 Efineptakin alfa Activator 99.70% Phase 2
HY-P991424 GSK2618960 Inhibitor 95.66% Phase 2
HY-P990647 PF-06342674 Inhibitor 99.69% Phase 1

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-206870 BP79 Inhibitor / Unkown
HY-167153 PNA5 / Unkown
HY-RS06779 IL7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS06780 IL7R Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174597 Human IL7R mRNA / Unkown
HY-174598 Human IL7 mRNA / Unkown
HY-RS16894 Il7r Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17031 Il7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23336 Il7r Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23475 Il7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990774 Verekitug Inhibitor 97.00% Unkown
HY-P990210 Anti-Mouse/Human IL-7 Antibody (M25) Inhibitor 98.43% Unkown
HY-P990911 Crebankitug Inhibitor ≥99.0% Unkown
HY-P990209 Anti-Mouse IL-7Rα/CD127 Antibody (A7R34) Inhibitor 95.00% Unkown
HY-P991720 Tepilukimig Inhibitor 95.57% Unkown
HY-P990292 Anti-Mouse CD132 (common γ chain) Antibody (3E12) Inhibitor / Unkown
HY-P991265 OSE-703 Inhibitor / Unkown
HY-P992447 QX008N Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il7 NCBI NCBI:3574