NMT1 - Nmt1 N-myristoyltransferase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 259274

Summary

Enables myristoyltransferase activity. Predicted to be involved in N-terminal peptidyl-glycine N-myristoylation and cellular ketone metabolic process. Predicted to act upstream of or within N-terminal protein myristoylation and in utero embryonic development. Predicted to be located in cytosol and plasma membrane. Predicted to be extrinsic component of membrane. Predicted to be active in cytoplasm. Orthologous to human NMT1 (N-myristoyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]

NMT1 Products (1)

mRNA Protein Name
NM_148891.2 NP_683689.1 glycylpeptide N-tetradecanoyltransferase 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables myristoyltransferase activity IDA
IDA: Inferred from direct assay
12210757 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycylpeptide N-tetradecanoyltransferase 1

  • NMT 1

  • myristoyl-CoA:protein N-myristoyltransferase 1

  • peptide N-myristoyltransferase 1

  • type I N-myristoyltransferase

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-147308 Zelenirstat Inhibitor 99.76% Phase 1

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112258 IMP-1088 Inhibitor 98.84% Unkown
HY-P6028A GSNKSKPK-NH2 TFA Substrate 99.91% Unkown
HY-P6028 GSNKSKPK-NH2 Substrate 98.00% Unkown
HY-RS09389 NMT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18960 Nmt1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25450 Nmt1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NMT1 NCBI NCBI:4836