EHF - ETS homologous factor Gene

Homo sapiens

Also known as ESE3; ESEJ; ESE3B

Gene ID: 26298 | Gene type: protein coding

About EHF

Cytogenetic location: 11p13 Genomic coordinates (GRCh38): 11:34,621,093-34,663,288 (from NCBI)

This gene has 12 transcripts (splice variants), 205 orthologues and 28 paralogues. Biased expression in esophagus (RPKM 89.9), colon (RPKM 60.6) and 12 other tissues.

Summary

This gene encodes a protein that belongs to an ETS transcription factor subfamily characterized by epithelial-specific expression (ESEs). The encoded protein acts as a transcriptional repressor and may be involved in epithelial differentiation and carcinogenesis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2011]

EHF Products(19)

mRNA	Protein	Name
NM_001206615.2	NP_001193544.1	ETS homologous factor isoform 3
NM_001206616.2	NP_001193545.1	ETS homologous factor isoform 1 precursor
NM_001378041.1	NP_001364970.1	ETS homologous factor isoform 2
NM_001378042.1	NP_001364971.1	ETS homologous factor isoform 2
NM_001378043.1	NP_001364972.1	ETS homologous factor isoform 2
NM_001378044.1	NP_001364973.1	ETS homologous factor isoform 2
NM_001378045.1	NP_001364974.1	ETS homologous factor isoform 2
NM_001378046.1	NP_001364975.1	ETS homologous factor isoform 2
NM_001378047.1	NP_001364976.1	ETS homologous factor isoform 2
NM_001378048.1	NP_001364977.1	ETS homologous factor isoform 3
NM_001378049.1	NP_001364978.1	ETS homologous factor isoform 4
NM_001378050.1	NP_001364979.1	ETS homologous factor isoform 4
NM_001378051.1	NP_001364980.1	ETS homologous factor isoform 4
NM_001378052.1	NP_001364981.1	ETS homologous factor isoform 5 precursor
NM_001378053.1	NP_001364982.1	ETS homologous factor isoform 6
NM_001378054.1	NP_001364983.1	ETS homologous factor isoform 7
NM_001378055.1	NP_001364984.1	ETS homologous factor isoform 8
NM_001378056.1	NP_001364985.1	ETS homologous factor isoform 9
NM_012153.6	NP_036285.2	ETS homologous factor isoform 2

EHF Protein Structure

SAM_PNT

Ets

0
100
200
300 a.a.

Protein Preferred Names

Protein Names

ETS homologous factor

ESE3 transcription factor

Related Diseases

Diseases

Alias

Allergic Urticaria

Infiltrative Basal Cell Carcinoma

Skin Infiltrating Basal Cell Carcinoma

Milk Allergy

Milk Allergic Reaction	Milk Hypersensitivity
Allergy Milk

Cow Milk Allergy

Bos Taurus Milk Allergy

Cow'S Milk Protein Sensitivity

Cystic Fibrosis

Mucoviscidosis	CF
Pseudomonas Aeruginosa, Susceptibility To Chronic Infection By, In Cystic Fibrosis	Pseudomonas Aeruginosa Chronic Infection By, In Cystic Fibrosis
Cystic Fibrosis Lung Disease, Modifier Of	Cystic Fibrosis Of Pancreas
Fibrocystic Disease Of Pancreas	Cf - [Cystic Fibrosis]
Cystic Fibrosis Nos	Fibrocystic Disease
Fibrocystic Disease Of The Pancreas	Mucoviscidosis Of Pancreas
Nonproliferative Fibrocystic Disease	Pancreatic Cystic Fibrosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04225	EHF Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Canis familiaris	EHF	VGNC	VGNC:40249
Felis catus	EHF	VGNC	VGNC:102879
Macaca mulatta	EHF	VGNC	VGNC:72178
Mus musculus	EHF	MGD	MGI:1270840
Bos taurus	EHF	VGNC	VGNC:28375
Rattus norvegicus	EHF	RGD	RGD:1310282