Map3k2 - mitogen-activated protein kinase kinase kinase 2 Gene

Also Known as Mekk2; Mekk2b; 9630061B06Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 26405

Summary

Predicted to enable MAP kinase kinase kinase activity and protein kinase binding activity. Predicted to be involved in positive regulation of transcription, DNA-templated and protein phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; integumental system; respiratory system; and sensory organ. Orthologous to human MAP3K2 (mitogen-activated protein kinase kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Map3k2 Products (1)

mRNA Protein Name
NM_011946.3 NP_036076.2 mitogen-activated protein kinase kinase kinase 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12912994 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mitogen-activated protein kinase kinase kinase 2

  • MAP/ERK kinase kinase 2

  • MAPK/ERK kinase kinase 2

  • MEK kinase 2

  • MEKK 2

  • protein kinase MEKK2b

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-112080A (R)-BAY-6035 Inhibitor / Unkown
HY-RS08054 MAP3K2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21882 Map3k2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28399 Map3k2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Map3k2 NCBI NCBI:10746