SCG3 - secretogranin III Gene

Homo sapiens

Also known as SGIII

Gene ID: 29106 | Gene type: protein coding

About SCG3

Cytogenetic location: 15q21.2 Genomic coordinates (GRCh38): 15:51,681,503-51,721,026 (from NCBI)

This gene has 3 transcripts (splice variants) and 203 orthologues. Biased expression in brain (RPKM 94.6), adrenal (RPKM 8.5) and 1 other tissue.

Summary

The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active Peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

SCG3 Products(2)

mRNA	Protein	Name
NM_001165257.2	NP_001158729.1	secretogranin-3 isoform 2
NM_013243.4	NP_037375.2	secretogranin-3 isoform 1 precursor

SCG3 Protein Structure

SGIII

0
100
200
300
400
468 a.a.

Protein Preferred Names

Protein Names

secretogranin-3

Recombinant SCG3 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71279	SCG3/Secretogranin-3 Protein, Human (449a.a, HEK293, His)	Q8WXD2 (F20-L468)	≥95%
HY-P74568	SCG3/Secretogranin-3 Protein, Human (468a.a, HEK293, His,solution)	Q8WXD2 (M1-L468)	≥95%

Related Diseases

Diseases

Alias

Motility-Related Diarrhea

Exudative Vitreoretinopathy 1

Retinopathy Of Prematurity	Retrolental Fibroplasia
EVR1	Criswick-Schepens Syndrome
Rop	Exudative Vitreoretinopathy, Familial, Autosomal Dominant
Fevr, Autosomal Dominant	Premature Retinopathy
Vitreoretinopathy, Exudative 1	Autosomal Dominant Familial Exudative Vitreoretinopathy
Fevr	Vitreoretinopathy, Exudative, Type 1
Retinopathy Of Prematurity Nos	Rlf- [Retrolental Fibroplasia]
Rop - [Retinopathy Of Prematurity]	Terry Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS12502	SCG3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SCG3	VGNC	VGNC:34333
Canis familiaris	SCG3	VGNC	VGNC:45906
Rattus norvegicus	SCG3	RGD	RGD:621209
Mus musculus	SCG3	MGD	MGI:103032
Macaca mulatta	SCG3	VGNC	VGNC:77013
Felis catus	SCG3	VGNC	VGNC:64909
Macaca fascicularis	SCG3	NCBI
Others	SCG3	NCBI