Epha3 - Eph receptor A3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29210

Summary

Predicted to enable GPI-linked Ephrin Receptor activity; growth factor binding activity; and transmembrane-ephrin receptor activity. Involved in fever generation; response to cytokine; and response to lipopolysaccharide. Predicted to be located in several cellular components, including GABA-ergic synapse; early endosome; and nucleus. Predicted to be part of receptor complex. Predicted to be active in neuron projection and presynapse. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human EphA3 (EPH receptor A3). [provided by Alliance of Genome Resources, Apr 2022]

Epha3 Products (1)

mRNA Protein Name
NM_031564.2 NP_113752.2 ephrin type-A receptor 3 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
9458884 RGD
involved in fever generation IEP
IEP: Inferred from expression pattern
15671251 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
15671251 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 3

  • EK4

  • EPH-like kinase 4

  • rEK4

  • tyrosine-protein kinase TYRO4

  • tyrosine-protein kinase receptor REK4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (10)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18832 AWL-II-38.3 Inhibitor 99.68% Unkown
HY-148061 DB1113 99.86% Unkown
HY-148063 DB0614 99.92% Unkown
HY-170517 PKMYT1-IN-8 Inhibitor 99.31% Unkown
HY-146375 UniPR505 Antagonist 99.68% Unkown
HY-P10579 123B9 Agonist 99.67% Unkown
HY-10654 EphB4-IN-2 Inhibitor / Unkown
HY-RS04427 EPHA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18813 Epha3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25303 Epha3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha3 NCBI NCBI:2042