Otub1 - OTU deubiquitinase, ubiquitin aldehyde binding 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 293705

Summary

Predicted to enable ubiquitin binding activity; ubiquitin protein Ligase binding activity; and ubiquitin-like protein-specific protease activity. Involved in cellular response to interleukin-1. Located in cytoplasm and nucleus. Orthologous to human OTUB1 (OTU Deubiquitinase, ubiquitin aldehyde binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Otub1 Products (1)

mRNA Protein Name
NM_001106332.1 NP_001099802.1 ubiquitin thioesterase OTUB1

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in cellular response to interleukin-1 IEP
IEP: Inferred from expression pattern
22279542 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin thioesterase OTUB1

  • OTU domain, ubiquitin aldehyde binding 1

  • OTU domain-containing ubiquitin aldehyde-binding protein 1

  • deubiquitinating enzyme OTUB1

  • otubain-1

  • ubiquitin-specific-processing protease OTUB1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (19)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151563 OTUB1/USP8-IN-1 Inhibitor 98.31% Unkown
HY-151563A OTUB1/USP8-IN-1 TFA Inhibitor 99.56% Unkown
HY-143345 EN523 Ligand 99.22% Unkown
HY-115878 NJH-2-057 Modulator 98.84% Unkown
HY-144999 LEB-03-146 98.08% Unkown
HY-143344 NJH-2-056 Modulator 98.31% Unkown
HY-143340 LEB-03-145 / Unkown
HY-143342 LEB-03-144 / Unkown
HY-143343 LEB-03-153 / Unkown
HY-162966 MS7829 Activator / Unkown
HY-162967 MS8588 Degrader / Unkown
HY-175934 MS5105 Ligand / Unkown
HY-182350 FXR DUBTAC modulator-1 Modulator / Unkown
HY-183724 MS8572 Ligand / Unkown
HY-183725 MS5128 Modulator / Unkown
HY-185122 MS6178 Activator / Unkown
HY-RS09869 OTUB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16735 Otub1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23172 Otub1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Otub1 NCBI NCBI:55611