Nuak1 - NUAK family kinase 1 Gene

Also Known as RGD1309956

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 299694

About Nuak1

Primary_assembly 7: 19,329,933-19,401,913 forward strand.mRatBN7.2:CM026980.1

This gene has 1 transcript (splice variant), 257 orthologues, 26 paralogues and is associated with 2 phenotypes. Biased expression in Lung (RPKM 126.), Heart (RPKM 112.2) and 9 other tissues.

Summary

Predicted to enable p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to glucose starvation; regulation of cellular senescence; and regulation of myosin-light-chain-phosphatase activity. Predicted to be located in fibrillar center; microtubule cytoskeleton; and nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human NUAK1 (NUAK family kinase 1). [provided by Alliance of Genome Resources, Apr 2022]

Nuak1 Products (1)

mRNA Protein Name
NM_001106774.1 NP_001100244.1 NUAK family SNF1-like kinase 1

Nuak1 Protein Structure

STKc_NUAK

STKc_NUAK: cd14073 (53 - 306)

  • 0
  • 200
  • 400
  • 600
  • 661 a.a.
Protein Preferred Names Protein Names

NUAK family SNF1-like kinase 1

  • AMPK-related protein kinase 5

  • NUAK family, SNF1-like kinase, 1

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-12624 Narazaciclib Inhibitor 98.66% Phase 1

Pre-clinical Phase

Bioactive Molecules (9)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-12334 HTH-01-015 Inhibitor 99.10% Unkown
HY-15802 WZ4003 Inhibitor 98.22% Unkown
HY-120877 MRT199665 Inhibitor 99.85% Unkown
HY-153103 LRRK2/NUAK1/TYK2-IN-1 Inhibitor / Unkown
HY-153058 LRRK2-IN-8 Inhibitor / Unkown
HY-182743 OICR19451 Inhibitor / Unkown
HY-178171 ARUK2010489 Inhibitor 96.64% Unkown
HY-182361 NUAK1-IN-3 Inhibitor / Unkown
HY-178168 ARUK2010694 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nuak1 NCBI NCBI:9891