Samhd1 - SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 311580

Summary

Predicted to enable several functions, including dGTP binding activity; dGTPase activity; and nucleic acid binding activity. Predicted to be involved in several processes, including DNA metabolic process; protein homotetramerization; and purine deoxyribonucleoside triphosphate catabolic process. Predicted to be located in nucleoplasm; site of double-strand break; and tetraspanin-enriched microdomain. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Chilblain lupus; acute myeloid leukemia; hepatitis B; and hepatitis C. Orthologous to human SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Samhd1 Products (1)

mRNA Protein Name
NM_001191743.1 NP_001178672.1 deoxynucleoside triphosphate triphosphohydrolase SAMHD1
Protein Preferred Names Protein Names

deoxynucleoside triphosphate triphosphohydrolase SAMHD1

  • SAM domain and HD domain, 1

  • SAM domain and HD domain-containing protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-B1299A Cephalosporin C zinc salt Inhibitor 99.31% Unkown
HY-161296 TH6342 Inhibitor 99.15% Unkown
HY-RS12433 SAMHD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-137613 Sp-TTPαS Inhibitor / Unkown
HY-137613A Sp-TTPαS tetrasodium Inhibitor / Unkown
HY-137618A Sp-dGTPαS tetrasodium / Unkown
HY-137618B Rp-dGTPαS / Unkown
HY-137619A Sp-dCTPαS tetrasodium / Unkown
HY-182970 PROTAC SAMHD1 Degrader-1 Inhibitor / Unkown
HY-182973 SAMHD1 ligand-1 / Unkown
HY-182974 DCAF1 binder 3 / Unkown
HY-182975 E3 Ligase Ligand-linker Conjugate 229 / Unkown
HY-RS17783 Samhd1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24250 Samhd1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Samhd1 NCBI NCBI:25939