Igf2bp2 - insulin-like growth factor 2 mRNA binding protein 2 Gene

Also Known as Imp2; IMP-2; Neilsen; C330012H03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 319765

Summary

Predicted to enable mRNA 3'-UTR binding activity and mRNA 5'-UTR binding activity. Predicted to be involved in nervous system development; regulation of RNA metabolic process; and regulation of gene expression. Predicted to act upstream of or within mRNA transport and regulation of translation. Predicted to be located in Cytoskeleton. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; early conceptus; gonad; liver; and otocyst. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human IGF2BP2 (Insulin like growth factor 2 mRNA binding protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Igf2bp2 Products (1)

mRNA Protein Name
NM_183029.2 NP_898850.2 insulin-like growth factor 2 mRNA-binding protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
25863250 MGI
enables mRNA 5'-UTR binding IDA
IDA: Inferred from direct assay
25863250 MGI
enables translation regulator activity, nucleic acid binding IMP
IMP: Inferred from mutant phenotype
25863250 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within cold-induced thermogenesis IMP
IMP: Inferred from mutant phenotype
25863250 MGI
acts upstream of or within energy homeostasis IMP
IMP: Inferred from mutant phenotype
25863250 MGI
involved in negative regulation of translation IMP
IMP: Inferred from mutant phenotype
25863250 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

insulin-like growth factor 2 mRNA-binding protein 2

  • IGF-II mRNA-binding protein 2

  • IGF2 mRNA-binding protein 2

  • VICKZ family member 2

  • insulin-like growth factor 2, binding protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-153274 CWI1-2 Inducer 98.85% Unkown
HY-153274A CWI1-2 hydrochloride Inducer 98.27% Unkown
HY-RS06620 IGF2BP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181666 Z971169476 / Unkown
HY-RS16822 Igf2bp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23262 Igf2bp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Igf2bp2 NCBI NCBI:10644