Mafa - v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) Gene

Also Known as RIPE3b1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 378435

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of transcription, DNA-templated. Located in nucleus. Is expressed in several structures, including lens vesicle; myotome; nervous system; pancreas; and spleen. Used to study maturity-onset diabetes of the young and type 2 diabetes mellitus. Orthologous to human MAFA (MAF bZIP transcription factor A). [provided by Alliance of Genome Resources, Apr 2022]

Mafa Products (1)

mRNA Protein Name
NM_194350.2 NP_919331.1 transcription factor MafA

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
12368292 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
12368292 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
12368292 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
12368292 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12917329 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
12368292 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12368292 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcription factor MafA

  • Mafa homolog

  • V-maf musculoaponeurotic fibrosarcoma oncogene homolog A

  • pancreatic beta-cell-specific transcriptional activator

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07397 KLRG1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-N19830 Guavenoic acid Inhibitor / Unkown
HY-RS07958 MAFA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174585 Human MAFA mRNA / Unkown
HY-RS17468 Klrg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19615 Mafa Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23926 Klrg1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26110 Mafa Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mafa NCBI NCBI:389692