ORM2 - orosomucoid 2 Gene

Also Known as AGP2; AGP-B; AGP-B'

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 5005

About ORM2

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:114,329,869-114,333,251 (from NCBI)

This gene has 1 transcript (splice variant), 126 orthologues and 1 paralogue. Restricted expression toward liver (RPKM 2828.2).

Summary

This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression. [provided by RefSeq, Jul 2008]

ORM2 Products (1)

mRNA Protein Name
NM_000608.4 NP_000599.1 alpha-1-acid glycoprotein 2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28514442 GOA
Biological Process GO Annotation Evidence References Source
involved in positive regulation of interleukin-1 beta production IDA
IDA: Inferred from direct assay
8774350 GOA
involved in positive regulation of interleukin-1 production IDA
IDA: Inferred from direct assay
8774350 GOA
involved in positive regulation of tumor necrosis factor production IDA
IDA: Inferred from direct assay
8774350 GOA
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
8774350 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ORM2 Protein Structure

Lipocalin

Lipocalin: Lipocalin / cytosolic fatty-acid binding protein family (40 - 179)

  • 0
  • 100
  • 201 a.a.
Protein Preferred Names Protein Names

alpha-1-acid glycoprotein 2

  • AGP 2

ORM2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ORM2 P19652 ORM1 Homo sapiens P02763
Anti Tag CoIP
33961781
Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant ORM2 Proteins

Cat. No. Product Name Accession Purity
HY-P7490 Orm2 Protein, Human (HEK293, His) P19652 (Q19-S201) ≥ 95%, as determined by reducing SDS-PAGE.

ORM2 Antibodies

Cat. No. Product Name Application Reactivity
HY-P83609 ORM2 Antibody (YA3354) WB, IHC-P Human
HY-P83609A ORM2 Antibody (YA3354)(PBS only) WB, IHC-P Human

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09832 ORM2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19150 Orm2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown