TPPP3 - tubulin polymerization promoting protein family member 3 Gene
Also Known as p20; CGI-38; TPPP/p20; p25gamma
生物種: Homo sapiens
About TPPP3
This gene has 5 transcripts (splice variants), 197 orthologues and 2 paralogues. Broad expression in lung (RPKM 89.8), placenta (RPKM 51.0) and 18 other tissues.
Summary
Enables tubulin binding activity. Involved in decidualization and microtubule bundle formation. Colocalizes with microtubule bundle and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
TPPP3 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_015964.4 | NP_057048.2 | tubulin polymerization-promoting protein family member 3 |
| NM_016140.4 | NP_057224.2 | tubulin polymerization-promoting protein family member 3 |
TPPP3 Protein Structure
p25-alpha: p25-alpha (10 - 173)
- 0
- 100
- 176 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
tubulin polymerization-promoting protein family member 3 |
|
Recombinant TPPP3 Proteins
| 製品番号 | 製品名 | アクセッション番号 | 純度 |
|---|---|---|---|
| HY-P77254 | TPPP3 Protein, Human (His) | Q9BW30 (M1-K176) | ≥ 95%, as determined by reducing SDS-PAGE. |
関連疾患
| Diseases | Alias | |
|---|---|---|
| Creutzfeldt-Jakob Disease |
|
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| Huntington Disease |
|
|
| Bardet-Biedl Syndrome 1 |
|
|
| Familial Apolipoprotein C-Ii Deficiency |
|
|
| Parkinson Disease, Late-Onset |
|
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Orthologs Information
| 生物種 | Symbol | 由来 | ID |
|---|---|---|---|
| Rattus norvegicus | TPPP3 | RGD | RGD:1305061 |
| Macaca mulatta | TPPP3 | VGNC | VGNC:104762 |
| Bos taurus | TPPP3 | VGNC | VGNC:36260 |
| Mus musculus | TPPP3 | MGD | MGI:1915221 |
| Felis catus | TPPP3 | VGNC | VGNC:66483 |
| Canis familiaris | TPPP3 | VGNC | VGNC:47751 |
| Others | TPPP3 | NCBI |