TPPP3 - tubulin polymerization promoting protein family member 3 Gene

Also Known as p20; CGI-38; TPPP/p20; p25gamma

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 51673

About TPPP3

Cytogenetic location: 16q22.1 Genomic coordinates (GRCh38): 16:67,389,809-67,393,498 (from NCBI)

This gene has 5 transcripts (splice variants), 197 orthologues and 2 paralogues. Broad expression in lung (RPKM 89.8), placenta (RPKM 51.0) and 18 other tissues.

Summary

Enables tubulin binding activity. Involved in decidualization and microtubule bundle formation. Colocalizes with microtubule bundle and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

TPPP3 Products (2)

mRNA Protein Name
NM_015964.4 NP_057048.2 tubulin polymerization-promoting protein family member 3
NM_016140.4 NP_057224.2 tubulin polymerization-promoting protein family member 3

TPPP3 Protein Structure

p25-alpha

p25-alpha: p25-alpha (10 - 173)

  • 0
  • 100
  • 176 a.a.
Protein Preferred Names Protein Names

tubulin polymerization-promoting protein family member 3

  • brain specific protein

Recombinant TPPP3 Proteins

Cat. No. Product Name Accession Purity
HY-P77254 TPPP3 Protein, Human (His) Q9BW30 (M1-K176) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Creutzfeldt-Jakob Disease

  • Variant Creutzfeldt-Jakob Disease

  • CJD

  • Bovine Spongiform Encephalopathy

  • Vcjd

  • Inherited Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Disease, Familial

  • Creutzfeldt Jakob Disease

  • Creutzfeldt-Jacob Disease

  • Creutzfeldt Jacob Disease

  • Sporadic Creutzfeldt-Jakob Disease

  • Encephalopathy, Bovine Spongiform

  • Creutzfeldt-Jakob Disease, Variant, Resistance To

  • Creutzfeldt-Jakob Disease, Variant

  • Creutzfeldt Jacob Syndrome

  • Jakob-Creutzfeldt Disease

  • Subacute Spongiform Encephalopathy

  • Transmissible Virus Dementia

  • New Variant Of Cjd

  • Nv-Cjd

  • Variant Cjd

  • Variant Creutzfeldt-Jacob Disease

  • Sporadic Cjd

  • Inherited Cjd

  • Acquired Creutzfeldt-Jakob Disease

  • Variant Mcj

  • Encephalopathy Bovine Spongiform

  • Familial Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Syndrome

  • New Variant Creutzfeldt-Jakob Disease

  • Creutzfeldt-Jakob Disease, Sporadic

  • Acquired Cjd

  • Scjd - [Sporadic Creutzfeldt-Jakob Disease]

  • Idiopathic Creutzfeldt-Jakob Disease

  • Creutzfeld-Jakob Disease Nos

  • Vcjd - [Variant Creutzfeldt-Jakob Disease]
Huntington Disease

  • Huntington'S Disease

  • Huntington Chorea

  • Huntington'S Chorea

  • HD

  • Huntington Chronic Progressive Hereditary Chorea

  • Juvenile Huntington Disease

  • Chronic Progressive Chorea

  • Chronic Progressive Hereditary Chorea

  • Hc - [Huntington Chorea]

  • Hereditary Chorea

  • Progressive Hereditary Chorea
Bardet-Biedl Syndrome 1

  • BBS1

  • Bardet-Biedl Syndrome 1, Modifier Of

  • Bardet-Biedl Syndrome

  • BBS

  • Bardet-Biedl Syndrome, Type 1

  • Laurence-Moon-Bardet-Biedl Syndrome
Familial Apolipoprotein C-Ii Deficiency

  • Familial Apoc-Ii Deficiency

  • Familial Apoc2 Deficiency

  • C-Ii Anapolipoproteinemia

  • Hyperlipoproteinemia, Type 1b

  • Hyperlipoproteinemia, Type Ib

  • Hyperlipoproteinemia Type I
Parkinson Disease, Late-Onset

  • Parkinson Disease

  • Parkinson'S Disease

  • PD

  • PARK

  • Parkinson Disease, Susceptibility To

  • Late Onset Parkinson'S Disease

  • Late Onset Parkinson Disease

  • Paralysis Agitans

  • Primary Parkinsonism

  • Idiopathic Parkinson Disease

  • Parkinson'S

  • Parkinson Disease, Late-Onset, Susceptibility To

  • Parkinson Disease, Age Of Onset, Modifier

  • Lewy Body Parkinson Disease

  • Idiopathic Parkinson'S Disease

  • Pd - [Parkinson Disease]

  • Parkinson Disease Nos

  • Parkinson, Nos

  • Primary Parkinson Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14945 TPPP3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19487 Tppp3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25981 Tppp3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus TPPP3 RGD RGD:1305061
Macaca mulatta TPPP3 VGNC VGNC:104762
Bos taurus TPPP3 VGNC VGNC:36260
Mus musculus TPPP3 MGD MGI:1915221
Felis catus TPPP3 VGNC VGNC:66483
Canis familiaris TPPP3 VGNC VGNC:47751
Others TPPP3 NCBI