PGM5 - phosphoglucomutase 5 Gene

Homo sapiens

Also known as PGMRP

Gene ID: 5239 | Gene type: protein coding

About PGM5

Cytogenetic location: 9q21.11 Genomic coordinates (GRCh38): 9:68,356,611-68,531,061 (from NCBI)

This gene has 7 transcripts (splice variants), 208 orthologues and 6 paralogues. Broad expression in prostate (RPKM 50.4), esophagus (RPKM 35.1) and 15 other tissues.

Summary

Phosphoglucomutases (EC 5.2.2.2.), such as PGM5, are phosphotransferases involved in interconversion of glucose-1-phosphate and glucose-6-phosphate. PGM activity is essential in formation of carbohydrates from glucose-6-phosphate and in formation of glucose-6-phosphate from galactose and glycogen (Edwards et al., 1995 [PubMed 8586438]).[supplied by OMIM, Mar 2008]

PGM5 Products(1)

mRNA	Protein	Name
NM_021965.4	NP_068800.2	phosphoglucomutase-like protein 5

PGM5 Protein Structure

PGM_PMM_I

PGM_PMM_II

PGM_PMM_III

0
100
200
300
400
500
567 a.a.

Protein Preferred Names

Protein Names

phosphoglucomutase-like protein 5

PGM-RP

Related Diseases

Diseases

Alias

Noonan Syndrome 10

NS10	Noonan Syndrome, Type 10

Breast Angiosarcoma

Angiosarcoma Of The Breast	Hemangiosarcoma Of The Breast
Primary Angiosarcoma Of Breast

Myopathy, Myofibrillar, 5

Myofibrillar Myopathy 5	MFM5
Myopathy, Myofibrillar, Filamin C-Related	Filaminopathy, Autosomal Dominant
Filaminopathy	Muscle Filaminopathy
Autosomal Dominant Filaminopathy	Mfm Filamin C-Related
Myopathy Myofibrillar Filamin C-Related	Myopathy, Myofibrillar, Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10393	PGM5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	PGM5	VGNC	VGNC:68820
Rattus norvegicus	PGM5	RGD	RGD:1307969
Mus musculus	PGM5	MGD	MGI:1925668
Canis familiaris	PGM5	VGNC	VGNC:49942
Macaca mulatta	PGM5	VGNC	VGNC:75971
Bos taurus	PGM5	VGNC	VGNC:32797