Chst3 - carbohydrate sulfotransferase 3 Gene

Also Known as C6ST; GST-0; C6ST-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 53374

Summary

Enables chondroitin 6-sulfotransferase activity and proteoglycan sulfotransferase activity. Acts upstream of or within T cell homeostasis and chondroitin sulfate biosynthetic process. Predicted to be located in Golgi membrane. Predicted to be integral component of membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and respiratory system. Used to study schizophrenia. Human ortholog(s) of this gene implicated in osteochondrodysplasia and spondyloepiphyseal dysplasia with congenital joint dislocations. Orthologous to human CHST3 (carbohydrate sulfotransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

Chst3 Products (2)

mRNA Protein Name
NM_001407025.1 NP_001393954.1 carbohydrate sulfotransferase 3
NM_016803.4 NP_058083.3 carbohydrate sulfotransferase 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chondroitin 6-sulfotransferase activity IDA
IDA: Inferred from direct assay
9597547 MGI
enables proteoglycan sulfotransferase activity IMP
IMP: Inferred from mutant phenotype
11696535 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within T cell homeostasis IMP
IMP: Inferred from mutant phenotype
11696535 MGI
acts upstream of or within chondroitin sulfate biosynthetic process IDA
IDA: Inferred from direct assay
9597547 MGI
involved in chondroitin sulfate biosynthetic process IDA
IDA: Inferred from direct assay
9597547 MGI
acts upstream of or within chondroitin sulfate biosynthetic process IMP
IMP: Inferred from mutant phenotype
11696535 MGI
Cellular Component GO Annotation Evidence References Source
is active in Golgi apparatus IDA
IDA: Inferred from direct assay
6781479 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

carbohydrate sulfotransferase 3

  • carbohydrate (chondroitin 6/keratan) sulfotransferase 3

  • chondroitin 6-O-sulfotransferase 1

  • chondroitin 6-sulfotransferase

  • galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 0

Recombinant Chst3 Proteins

Cat. No. Product Name Accession Purity
HY-P76259 CHST3 Protein, Mouse (HEK293, His) O88199 (E39-T472) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70163 Carbohydrate Sulfotransferase 3 / Unkown
HY-RS02689 CHST3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18383 Chst3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24864 Chst3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Chst3 NCBI NCBI:9469