Cd320 - CD320 antigen Gene

Also Known as 8D6; NG29; VLDL; TCblR; 425O18-1; D17Ertd716e

Species: Mus musculus

Gene Type: protein coding
Gene ID: 54219

Summary

Enables cargo receptor activity. Involved in cobalamin metabolic process. Acts upstream of or within regulation of vitamin metabolic process. Located in plasma membrane. Is expressed in several structures, including brain; genitourinary system; heart; immune system; and liver. Used to study methylmalonic acidemia due to transcobalamin receptor defect. Human ortholog(s) of this gene implicated in methylmalonic acidemia due to transcobalamin receptor defect. Orthologous to human CD320 (CD320 molecule). [provided by Alliance of Genome Resources, Apr 2022]

Cd320 Products (2)

mRNA Protein Name
NM_001305169.1 NP_001292098.1 CD320 antigen isoform 2 precursor
NM_019421.3 NP_062294.3 CD320 antigen isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables cargo receptor activity IMP
IMP: Inferred from mutant phenotype
23430977 MGI
Biological Process GO Annotation Evidence References Source
involved in cobalamin transport IMP
IMP: Inferred from mutant phenotype
23430977 MGI
acts upstream of or within regulation of vitamin metabolic process IMP
IMP: Inferred from mutant phenotype
23430977 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IMP
IMP: Inferred from mutant phenotype
23430977 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

CD320 antigen

  • putative VLDL lipoprotein receptor

  • transcobalamin receptor

Recombinant Cd320 Proteins

Cat. No. Product Name Accession Purity
HY-P76797 TCblR/CD320 Protein, Mouse (HEK293, Fc) Q9Z1P5-1 (M1-G208) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76798 TCblR/CD320 Protein, Mouse (HEK293, His) Q9Z1P5-1 (M1-G208) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02234 CD320 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17653 Cd320 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24113 Cd320 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cd320 NCBI NCBI:51293