Madcam1 - mucosal vascular addressin cell adhesion molecule 1 Gene
Species: Rattus norvegicus
Gene Type: protein coding
Gene ID: 54266
Summary
Predicted to enable Integrin binding activity involved in cell-matrix adhesion. Involved in aging; cell adhesion; and positive regulation of leukocyte migration. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Used to study Crohn's disease and food allergy. Orthologous to human MADCAM1 (mucosal vascular addressin cell adhesion molecule 1). [provided by Alliance of Genome Resources, Apr 2022]
Madcam1 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_019317.1 | NP_062190.1 | mucosal addressin cell adhesion molecule 1 precursor |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in cell adhesion |
IDA
IDA: Inferred from direct assay
|
12859728 | RGD |
| involved in positive regulation of leukocyte migration |
IMP
IMP: Inferred from mutant phenotype
|
14670821 | RGD |
EXP: Inferred from Experiment
IDA: Inferred from direct assay
IPI: Inferred from physical interaction
IMP: Inferred from mutant phenotype
IGI: Inferred from genetic interaction
IEP: Inferred from expression pattern
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
mucosal addressin cell adhesion molecule 1 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
Bioactive MoleculesInhibitory Antibodies
(1)
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-P99411 | Ontamalimab | 99.86% | Phase 3 |
Pre-clinical Phase
Bioactive Molecules
(6)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-159179 | α4 integrin receptor antagonist 3 | Inhibitor | / | Unkown |
| HY-171216 | GW559090 | Antagonist | / | Unkown |
| HY-177961 | α4β7 Integrin-IN-1 | Inhibitor | / | Unkown |
| HY-RS07952 | MADCAM1 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS19091 | Madcam1 Mouse Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
| HY-RS25581 | Madcam1 Rat Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Bioactive MoleculesInhibitory Antibodies
(3)
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-P990203 | Anti-Mouse LPAM-1/Integrin α4β7 Antibody (DATK32) | Inhibitor | 99.08% | Unkown |
| HY-P991807 | Anti-Mouse MAdCAM-1 Antibody (MECA-89) | Inhibitor | / | Unkown |
| HY-P990197 | Anti-Mouse MAdCAM-1 Antibody (MECA-367) | Inhibitor | 96.72% | Unkown |
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