PPID - peptidylprolyl isomerase D Gene

Homo sapiens

Also known as CYPD; CYP-40

Gene ID: 5481 | Gene type: protein coding

About PPID

Cytogenetic location: 4q32.1 Genomic coordinates (GRCh38): 4:158,709,127-158,723,396 (from NCBI)

This gene has 3 transcripts (splice variants), 243 orthologues and 22 paralogues. Ubiquitous expression in testis (RPKM 15.6), duodenum (RPKM 13.0) and 25 other tissues.

Summary

The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. [provided by RefSeq, Jul 2008]

PPID Products(1)

mRNA	Protein	Name
NM_005038.3	NP_005029.1	peptidyl-prolyl cis-trans isomerase D

PPID Protein Structure

Pro_isomerase

TPR_7

TPR_11

0
100
200
300
370 a.a.

Protein Preferred Names

Protein Names

peptidyl-prolyl cis-trans isomerase D

40 kDa peptidyl-prolyl cis-trans isomerase D

Recombinant PPID Proteins

Cat. No.	Product Name	Accession	Purity
HY-P71224	PPID Protein, Human (His)	Q08752 (M1-A370)	≥95%

Related Diseases

Diseases

Alias

Anaplastic Large Cell Lymphoma

Alcl	Cd30 Positive Anaplastic Large Cell Lymphoma
Ki-1 Positive Anaplastic Large Cell Lymphoma	Primary Systemic Alcl
Sacl	Ki-1+ Anaplastic Large Cell Lymphoma

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS10949	PPID Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	PPID	RGD	RGD:1303174
Bos taurus	PPID	VGNC	VGNC:33197
Canis familiaris	PPID	VGNC	VGNC:44851
Felis catus	PPID	VGNC	VGNC:79975
Mus musculus	PPID	MGD	MGI:1914988
Others	PPID	NCBI